Publications by authors named "Sander Kneepkens"
Article Synopsis
- The study aimed to explore the relationship between eye shape, volume measured via MRI and optical biometry, and spherical equivalent (SE) refractive error in children aged 10.
- It involved 3,637 participants and found myopic eyes had significantly larger posterior segment volumes than emmetropic and hyperopic eyes, with a notable correlation between posterior segment length and SE.
- The results indicated that most 10-year-olds had an oblate eye shape, though a significant number of myopic eyes were prolate, raising questions about the long-term implications of eye shape on myopia development that warrant further research.
Time Spent Outdoors Partly Accounts for the Effect of Education on Myopia.
Invest Ophthalmol Vis Sci
November 2023
Purpose: The purpose of this study was to investigate if education contributes to the risk of myopia because educational activities typically occur indoors or because of other factors, such as prolonged near viewing.
Methods: This was a two-sample Mendelian randomization study. Participants were from the UK Biobank, Avon Longitudinal Study of Parents and Children, and Generation R.
Background: High myopia (HM), defined as a spherical equivalent refractive error (SER) ≤ -6.00 diopters (D), is a leading cause of sight impairment, through myopic macular degeneration (MMD). We aimed to derive an improved polygenic score (PGS) for predicting children at risk of HM and to test if a PGS is predictive of MMD after accounting for SER.
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- - The study investigates how COVID-19 lockdowns in the Netherlands impacted myopia (nearsightedness) in teenagers, particularly regarding their nearwork activities and outdoor time.
- - Findings reveal that nearwork increased significantly during the lockdown, with time spent on non-educational activities rising by nearly 50%, while outdoor time remained relatively unchanged.
- - The increase in nearwork persisted even after lockdowns ended, suggesting a potential rise in myopia prevalence and progression among European children following the pandemic.
Cerebrovascular reactivity changes in acute concussion: a controlled cohort study.
Quant Imaging Med Surg
November 2021
Background: Evidence suggests that cerebrovascular reactivity (CVR) increases within the first week after the incidence of concussion, indicating a disruption of normal autoregulation. We sought to extend these findings by investigating the effects of acute concussion on the speed of CVR response and by visualizing global and regional impairments in individual patients with acute concussion.
Methods: Twelve patients aged 18-40 years who experienced concussion less than a week before this prospective study were included.