Publications by authors named "Sander H Bollen"
J Med Genet
November 2021
Article Synopsis
- Familial cases of melanoma may have a shared genetic predisposition, but only a small percentage show known high-risk gene variants.
- A study of Dutch familial melanoma patients found that a melanoma-specific Polygenic Risk Score (PRS) significantly correlates with melanoma risk, showing a greater risk in individuals with multiple melanomas.
- The findings highlight the potential of using PRS as a diagnostic tool for assessing melanoma risk in families with unexplained genetic factors, suggesting further research in this area is warranted.
