Similarities and Differences in Benzene Reduction with Ca, Sr, Yb and Sm: Strong Evidence for Tetra-Anionic Benzene.

Inverse sandwich complexes of Yb and Sm stabilized by a bulky β-diketiminate (BDI) ligand have been prepared: (BDI)Ln(η,η-CH)Ln(BDI); Ln=lanthanide. Coordinated benzene ligands can be neutral, di-anionic or, often controversially discussed, even tetra-anionic. The formal charge on benzene is correlated to assignment of the metal oxidation state which generally poses a problem.

Bistable Aryl Azopyrazolium Ionic Photoswitches in Water.

We report a new class of arylazopyrazolium-based ionic photoswitches (AAPIPs). These AAPIPs with different counter ions have been accessed through a modular synthetic approach in high yields. More importantly, the AAPIPs exhibit excellent reversible photoswitching and exceptional thermal stability in water.

Well-Defined Ni(0) and Ni(II) Complexes of Bicyclic (Alkyl)(Amino)Carbene ( BICAAC): Catalytic Activity and Mechanistic Insights in Negishi Cross-Coupling Reaction.

Negishi cross-coupling reaction of organozinc compounds as nucleophiles with aryl halides has drawn immense focus for C-C bond formation reactions. In comparison to the well-established library of Pd complexes, the C-C cross-coupling of this particular approach is largely primitive with nickel-complexes. Herein, we describe the syntheses of Ni(II) complexes, [( BICAAC) NiX ] (X=Cl (1), Br (2), and I (3)) by employing the bicyclic (alkyl)(amino)carbene ( BICAAC) ligand.

Structure-Property Relationship for Visible Light Bidirectional Photoswitchable Azoheteroarenes and Thermal Stability of -Isomers.

A modular approach has been adopted to synthesize a wide range of visible light-driven photoswitchable azoheteroarenes. In this regard, we considered substitution of cyclic amines in the aryl ring and varied substitution patterns. Using detailed spectroscopic studies, we established a relationship between structure and photoswitching ability and also half-lives of the -isomers.

The prevalence, severity, and risk factors for dry eye disease in Dubai - a cross sectional study.

Background: The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients' quality of life. No published studies on the epidemiology of dry eyes have been found in Dubai.

Purpose: To describe the epidemiology, prevalence, severity, and associated factors of dry eyes in Dubai, United Arab Emirates, in 2019.

Spatial and seasonal distribution of multi-elements in suspended particulate matter (SPM) in tidally dominated Hooghly river estuary and their ecotoxicological relevance.

The present work represented first study of the spatio-seasonal distribution of the multi-elements in the suspended particulate matter (SPM) of the tropical Hooghly river estuary (HRE), eastern part of India. The high load of SPM (20-3460 mg/l) might have induced negative impact on the phytoplankton density. The relative abundance of the studied elements exhibited the following decreasing trend (concentration in μg/g and %): Si(26.

Reactions of a BICAAC with hydroboranes: propensity for Lewis adduct formation and carbene insertion into the B-H bond.

The reactivity of a bicyclic (alkyl)(amino)carbene (BICAAC) towards different boranes has been examined in the present work. The reactions with boranes BX3·SMe2 (X = H, Cl, Br), BF3·OEt2 and BCl3 yield Lewis adducts [BICAAC·BH3] (1), [BICAAC·BHCl2] (2), [BICAAC·BH2Cl] (3), [BICAAC·BF3] (4), [BICAAC·BCl3] (5) and [BICAAC·BBr3] (6) respectively, whereas more hydridic boranes, 9-borabicyclo[3.3.

Neutral and cationic cyclic (alkyl)(amino)carbene mercury [cAAC-Hg(ii)] complexes: scope of hydroamination of alkynes with organomercury compounds.

This study demonstrates the first synthesis of cyclic (alkyl)(amino)carbene (cAAC) adducts of Hg(ii), [cAACMe·HgBr(μ-Br)]2 (1a) and [cAACcy·HgBr(μ-Br)]2 (1b). Adduct 1b catalyzes intermolecular hydroamination of aromatic alkynes and amines under mild conditions to afford aromatic imines. The quest to prepare an electrophilic Hg(ii) complex resulted in the synthesis of cationic [(cAACcy)2Hg(H2O)]2+2[NO3]- (3) by reacting 1b with AgNO3.

Implication of novel thiazolo-thiophene derivative (MCD-KV-10) for management of asthma.

Context: Asthma is multifaceted disease where many targets contribute towards its development and progression. Among these, adenosine receptor subtypes play a major role.

Objective: MCD-KV-10, a novel thiazolo-thiophene was designed and evaluated pre-clinically for its implication in management of asthma.

Evaluation of GABAergic Transmission Modulation as a Novel Functional Target for Management of Multiple Sclerosis: Exploring Inhibitory Effect of GABA on Glutamate-Mediated Excitotoxicity.

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS) where the communication ability of nerve cells in the brain and spinal cord with each other gets impaired. Some current findings suggest the role of glutamate excitotoxicity in the development and progression of MS. An excess release of glutamate leads to the activation of ionotropic and metabotropic receptors, thus resulting in accumulation of toxic cytoplasmic Ca(2+) and cell death.

Transpupillary thermotherapy for choroidal neovascular membrane in age related macular degeneration.

Purpose: To evaluate the efficacy of transpupillary thermotherapy (TTT) in choroidal neovasularisation (CNVM) secondary to age related macular degeneration (AMD).

Material And Methods: Retrospective, non-randomized study of 28 eyes of 28 patients with subfoveal CNVM (classic, occult or mixed) secondary to AMD.

Results: Fifteen patients (53.