Rucabarib: A new lease of life for ovarian cancer patients.

Background: Rucaparib is a drug with potential as maintenence monotherapy in ovarian cancers irrespective of genetic mutation.

Methods: The results of the ARIEL 3 trial were analysed for the drug's prospects towards cure in ovarian and other pelvic malignancies.

Results: Ovarian cancer patients with highly malignant tumors and relapses on platinum based chemotherapy exhibited statistically significant reductions in tumor size with maintenance Rucaparib therapy vis a vis placebo.

Personality traits as a predictor of emotional intelligence among medical students.

Introduction: Emotional intelligence (EI) is the ability to understand and manage our own feelings and of others. It has emerged as one of the vital elements of success and interpersonal relations in everyday life. There are individual differences of EI depending on characteristics and behaviors of an individual, which determines their personality.

Gender-based violence in New Delhi, India: forecast based on secondary data analysis.

Background: Violence against women is a global phenomenon.

Aims: To estimate and forecast cognizable crime against women in New Delhi, India, from 2016 to 2020.

Methods: Reported cognizable crime against women in New Delhi for 2009-2015 was extracted for statistical analysis, synthesis and modelling.

Primary acquired gastric outlet obstruction in children: A retrospective single center study.

Background/ Purpose: Idiopathic hypertrophic pyloric stenosis is by far the most common cause of gastric outlet obstruction (GOO) in young infants, with more than 90% of cases presenting between 3 and 10 weeks after birth. While cases of late onset pyloric stenosis beyond infancy have been reported, the etiology is poorly understood. We report our experience of 5 cases, describing the similarities and differences in management of our patient population which happens to be the second largest reported in literature.

Organ donation in India: Scarcity in abundance.

In modern era, India witnessed its first successful corneal, kidney and cardiac transplant in the year 1960, 1967 and 1994 though the reverberations for organ donation and transplantation (ODT) existed since time-memorial with roots existing in Hindu mythology along with vivid example of Guru Dadheech and lord Ganesha. No country in the world is able to meets its organ requirement. Government of India promulgated Transplantation of Human Organ and Tissues Act in 1994 and with the view to enlarge its scope and promote organ donation government has brought new amendments as of year 2014 and 2017.

Hemorrhagic pleural effusion due to pseudo-pancreatic cyst.

Hemorrhagic pleural effusion is a common clinical entity still diagnosis is often missed. An unusual and often over-looked cause of pleural effusion is an intra-abdominal process including complication arising due to pancreatitis. We report a rare case of massive left sided hemorrhagic pleural effusion in a patient due to pancreatic pathology.

Hypertension in Pregnancy: A Community-Based Study.

Background: Hypertensive disorders during pregnancy occur in women with preexisting primary or secondary chronic hypertension, and in women who develop new-onset hypertension in the second half of pregnancy. The present study was undertaken to study the prevalence and correlates of hypertension in pregnancy in a rural block of Haryana.

Materials And Methods: This cross-sectional study was carried out in the all 20 subcenters under Community Health Center (CHC) Chiri, Block Lakhanmajra.

Level of motivation amongst health personnel working in a tertiary care government hospital of new delhi, India.

Aims: To assess the level and factors of motivation amongst permanent government employees working in a tertiary health care institution.

Material And Methods: A sample of 200 health personnel (50 in each category) i.e.

Gross congenital malformation at birth in a government hospital.

A hospital-based cross-sectional study was undertaken to determine proportion of gross congenital malformation (GCMF) occurring at intramural births. Rate of GCMF was found to be 16.4/1000 consecutive singleton births (>28 weeks) with three leading malformation as anencephaly (44.

Early birth registration at a center in rural India.

Background: Registration of birth is mandatory in India however due to various issues compliance for timely birth registration has been poor.

Objective: The objective of this study was to determine time elapsed between birth and registration and describe the socio-demographic profile of registered births at a rural center.

Materials And Methods: A cross-sectional descriptive study was undertaken and all births registered at a primary health center of a block during the period 2010 and 2011 were retrieved and data collection carried using structured proforma based on birth formats under civil registration system (CRS).

Solitary fibrous tumour of lung.

Fibrous tumours arising entirely within the substance of the lung are rare. We report one such rare case in whom the diagnosis was established after surgical removal.

Birth audit.

Objective: To describe profile of births occurring in teaching institution on selected parameters.

Materials And Methods: Considering feasibility, four months were systematically chosen for two-year time frame over a decade to gather selected information of consecutive singleton intramural births from log books of labor room on structured pro-forma. Data management was done using software package and analysis carried out by computing descriptive statistics (%) and Chi-square test.

Body image satisfaction among female college students.

Objective: To determine body image satisfaction among newly entrant women students in a professional institution.

Materials And Methods: A cross-sectional study using body image satisfaction described in words was undertaken, which also explored relationship with body mass index (BMI) and other selected co-variables such as socio-demographic details, overall satisfaction in life, and particularly in academic/professional life, current health status using 5-item based Likert scale. Height, weight, hip and waist circumference measurement was carried out using standard protocol.

All Slums are Not Equal: Maternal Health Conditions Among Two Urban Slum Dwellers.

Background: Pregnant women inhabiting urban slums are a "high risk" group with limited access to health facilities. Hazardous maternal health practices are rampant in slum areas. Barriers to utilization of health services are well documented.

Diffuse proliferative crescentic lupus nephritis with normal renal function.

Crescentic nephritis can be a manifestation of Lupus Nephritis. It usually presents with rapid deterioration of renal functions over days to weeks with an active urinary sediment and confers a poor prognosis. Nephrotic range proteinuria is rare in crescentic nephritis.

Chronic urticaria.

Chronic urticaria (CU) is a disturbing allergic condition of the skin. Although frequently benign, it may sometimes be a red flag sign of a serious internal disease. A multitude of etiologies have been implicated in the causation of CU, including physical, infective, vasculitic, psychological and idiopathic.

Lifestyle and gallstone disease: scope for primary prevention.

Objective: To study the antecedent risk factors in the causation of gallstone disease in a hospital-based case control study.

Materials And Methods: Cases (n = 150) from all age groups and both sexes with sonographically proven gallstones were recruited over a duration of 3 months from the surgical wards of a tertiary care teaching hospital. Modes of presentation were also noted among cases.

HIV/AIDS knowledge among first year MBBS, Nursing, Pharmacy students of a health university, India.

Objective: To determine level of HIV/AIDS knowledge among first-year MBBS, nursing and pharmacy students of a health university.

Materials And Methods: A pre-designed, pre-tested, anonymous self-administered, semi-structured questionnaire was circulated among available 129, 53 and 55 first-year MBBS, nursing and pharmacy students during Oct' 09. Data entry, management and analysis were carried out using MS excel and software statistical package.