Publications by authors named "Sandeep Das"

A new species of the uropeltid ('shieldtail') snake genus Uropeltis is described based on eight specimens from the southern part of peninsular India's Western Ghats. Uropeltis caudomaculata sp. nov.

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Objective: To examine inpatient COVID-19-related outcomes among patients with and without diabetes alone or with a history of established heart failure (HF) or established atherosclerotic cardiovascular disease (ASCVD).

Design: Observational study; longitudinal analysis of registry data.

Setting: Hospitals in the USA reporting to the American Heart Association (AHA) COVID-19 Registry from January 2020 to May 2021.

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With 90 recognized species, kukri snakes in the genus Oligodon Fitzinger constitute the second largest snake radiation in the world. Oligodon species are collectively distributed across the Asian continent and possess several ecological and morphological attributes that are unique amongst other snakes. Despite their high levels of species richness, evolutionary relationships within Oligodon are poorly understood due to a limited number of samples and genetic markers available in earlier phylogenies.

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The incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.

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Background: Patients with metabolic dysfunction-associated steatohepatitis (MASH) are at an increased risk of developing venous thromboembolic events, including deep vein thrombosis (DVT). To date, the study of DVT in MASH has been hampered by the lack of reliable models that mimic the pathologic aspects of human disease.

Objectives: To evaluate DVT severity and hypercoagulability in murine and human MASH.

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Designing dual-ion batteries (DIBs) by using various electrolytes through experiments or computationally is highly time-consuming and needs high-cost sophisticated resources. Here, we have utilized the ultrafast screening capability of machine learning (ML) to search for suitable salt-electrolytes toward the design of DIBs, choosing voltage as the desirable descriptor. Considering 50 different salts and their suitable staging mechanisms, the XGBoost Regressor ML model has been found to perform with remarkable accuracy.

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The increasing global consumption of poultry meat has led to the generation of a vast quantity of feather keratin waste daily, posing significant environmental challenges due to improper disposal methods. A growing focus is on utilizing keratinous polymeric waste, amounting to millions of tons annually. Keratins are biochemically rigid, fibrous, recalcitrant, physiologically insoluble, and resistant to most common proteolytic enzymes.

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Background: The emergence and evolution of SARS-CoV-2 resulted a severe threat to public health globally. Due to the lack of an effective vaccine with durable immunity, the disease transited into the endemic phase, necessitating potent antiviral therapy including a scientific basis for current traditional herbal medicine.

Objective: This study aimed to conduct a pharmacoinformatic analysis of selected chemical ingredients and in-vitro evaluation of Cordyceps militaris extract against SARS-CoV-2.

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Background: Anthropometric assessment in the paediatric population is particularly important to assess the child's general health status, nutritional adequacy, and growth and developmental pattern. However, there are often shortcomings in the quality of anthropometric assessment done in primary healthcare settings despite the presence of established guidelines. In this study, we plan to use the quality improvement (QI) principles to improve the anthropometric assessment of under-5 children attending an urban primary health centre in Delhi, India.

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The tea plant, Camellia sinensis [L.] O. Kuntze, is a vital global agricultural commodity, yet faces challenges from fungal infections, which affects its production.

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Article Synopsis
  • Cardiogenic shock after acute myocardial infarction remains highly lethal, prompting researchers to analyze data from 16,337 cases across 440 centers to identify characteristics linked to lower mortality.
  • The study found that centers with lower risk-adjusted in-hospital mortality rates typically had patients with fewer co-morbidities, performed more revascularizations, and showed better adherence to clinical processes.
  • Despite the presence of some beneficial factors, not all low-mortality centers demonstrated these characteristics, indicating the complexity of treating cardiogenic shock and the challenges in evaluating outcomes in such cases.
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Advertisement calls in frogs have evolved to be species-specific signals of recognition and are therefore considered an essential component of integrative taxonomic approaches to identify species and delineate their distribution range. The species rich genus is a particularly challenging group for species identification, discovery and conservation management due to the small size, conserved morphology and wide distribution of its members, necessitating the need for a thorough description of their vocalization. In this study, we provide quantitative description of the vocal behaviour of , a widely distributed south Asian species, from Delhi, India, based on call recordings of 18 individuals and assessment of 21 call properties.

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Diabetes can be an arduous journey both for people with diabetes (PWD) and their caregivers. While the journey of every person with diabetes is unique, common themes emerge in managing this disease. To date, the experiences of PWD have not been fully considered to successfully implement the recommended standards of diabetes care in practice.

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The shieldtail snake Rhinophis fergusonianus Boulenger, 1896 was previously known only from the holotype specimen collected approximately 130 years ago from an imprecise Indian locality (Cardamom Hills). We report the rediscovery of this species from four localities, from low-elevation hills on both sides of the Palghat Gap in the southern part of the Western Ghats of peninsular India. We document new specimens of R.

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A molecular level understanding of the property evolution in binary nanoalloy catalysts is crucial for designing novel electrocatalysts for ammonia synthesis. In this regard, designing core-shell catalyst structures has been a versatile approach to achieve the product selectivity. Herein, we investigated the activity evolution of Fe-based core-shell (M@Fe) (M = Co, Ni, or Cu) clusters for the nitrogen reduction reaction (NRR).

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Dual-ion batteries (DIBs) represent a promising energy storage technology, offering a cost-effective safe solution with impressive electrochemical performance. The large combinatorial configuration space of the electrode-electrolyte leads to design challenges. We present a machine learning (ML) approach for accurately predicting the voltage and volume changes of polycyclic aromatic hydrocarbon (PAH) cathodes upon intercalation with a variety of DIB salts following different mechanisms.

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Article Synopsis
  • - Systematic assessments of species extinction risk are crucial for effective conservation, and the second Global Amphibian Assessment evaluated over 8,000 species for their threat levels.
  • - Amphibians are the most at-risk vertebrates, with 40.7% of species globally threatened, and their status has worsened since previous assessments, especially in salamanders and the Neotropics.
  • - The major threats contributing to declining amphibian populations include disease, habitat loss, and increasing impacts from climate change, highlighting the urgent need for more conservation funding and initiatives to reverse negative trends.
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Objectives: To characterize the long term risk of death and hospital readmission after an index admission with covid-19 among Medicare fee-for-service beneficiaries, and to compare these outcomes with historical control patients admitted to hospital with influenza.

Design: Retrospective cohort study.

Setting: United States.

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Article Synopsis
  • The study aimed to analyze healthcare costs over an individual's lifetime, focusing on those with cardiovascular risk factors and disparities among racial/ethnic groups and sexes.
  • Researchers used data from the Dallas Heart Study and healthcare claims to track healthcare expenses from ages 40 to 80, accounting for factors like race, sex, and risk indicators like diabetes and hypertension.
  • Results indicated that Black individuals faced significantly higher lifetime healthcare expenses than non-Black individuals, with other risk factors contributing to increased costs, particularly as individuals aged.
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Background: Impairments in carbohydrate, lipid, and amino acid metabolism drive features of plaque instability. However, where these impairments occur within the atheroma remains largely unknown. Therefore, we sought to characterize the spatial distribution of metabolites within stable and unstable atherosclerosis in both the fibrous cap and necrotic core.

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