Publications by authors named "Sanchez-Gonzalez E"
Liver extracellular matrix-based models that precisely reproduce liver physiology and functions are required as 3D culture microenvironments for multiple applications in toxicology and metabolism, or for understanding the mechanisms implicated in liver disease. We introduced injectable gelatin-chondroitin sulphate (Gel/CS) hydrogels for culturing HepG2 cells, and evaluated the mechanical properties and functionality of cells in different Gel/CS compositions. The Gel/CS hydrogels exhibited soft mechanical properties and allowed the HepG2 culture.
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- Continuous emission of harmful gases is detrimental to the environment, air quality, and public health, prompting the need for materials that can capture and deactivate these gases.
- The study introduces a breakthrough in porous materials, showing how varying counterions in PdL Metal-Organic Cages allows for switching between physisorption and chemisorption of sulfur oxides (SO), achieving reversible adsorption and high selectivity.
- Notably, a nitrate derivative of PdL can capture significant amounts of SO, efficiently convert it to a less harmful form, and be regenerated under humid conditions, paving the way for advanced applications in gas contamination management.
The archetypical metal-organic framework (MOF), HKUST-1, has been systematically modified in both its organic and inorganic building blocks to introduce diversity in the metal centers and create defects within the network, achieving a variety of bimetallic hierarchical structures. These modifications changed the affinity of the MOFs for acid gases. The introduction of bimetallic sites mostly affects CO adsorption, while the hierarchical structure generates an increase in SO uptake capacity, allowing better performance in the separation of binary mixtures of these gases near room temperature.
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- The study highlights the first experimental use of covalent organic frameworks (COFs) for detecting sulfur dioxide (SO2), showcasing SonoCOF-9 as a promising material.
- SonoCOF-9 achieved a reversible SO2 sorption capacity of 3.5 mmol g-1 at 1 bar and 298 K, with good performance over multiple cycles.
- The research combines experimental findings with molecular simulations, indicating that SonoCOF-9 interacts strongly with SO2, making it suitable for detecting low concentrations of the gas (as low as 0.0064 ppm).
Zirconia-reinforced lithium silicate (ZLS) is utilized as a material for prosthetic tooth crowns, offering enhanced strength compared to other dental glass-ceramics. In this study, we investigate a commercial ZLS material, provided in a fully crystallized form. We examine the effects of an optional post-processing heat treatment on micro-contact damage using controlled indentation tests simulating the primary modes of contact during chewing: axial and sliding.
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- SO emissions impact local air quality and contribute to broader environmental challenges, highlighting the need for effective solutions.
- Carbon microfibers (CMFs) are evaluated for their ability to adsorb and desorb SO, showing a substantial uptake capacity of 5 mmol/g.
- The study demonstrates CMFs' efficiency with fast kinetics, good selectivity for SO over CO, and consistent performance across ten adsorption cycles at room temperature.
Article Synopsis
- Excellent SO (sulfur oxides) capture by porous materials is emphasized, highlighting the importance of achieving uptake rates above 17 mmol g.
- The study focuses on a family of Al(III)-MOFs (Metal-Organic Frameworks) that resemble the MIL-53 structure and explores their SO adsorption behavior at low pressures.
- Results show an inversely proportional relationship between pore size and SO uptake, where larger channel pores lead to decreased SO capture, and this trend is further supported by both experimental and computational findings.
Article Synopsis
- The study explores a new method for controlled delivery of nitric oxide (NO) using metal-organic polyhedra (MOPs) to treat various diseases.
- The researchers utilize dirhodium paddlewheel complex-based MOPs (RhMOP) that allow NO to attach to specific sites, enhancing the control over its release.
- The release of NO from the created amorphous coordination polymer particles (CPPs) can be triggered by light and humidity, with factors like ligand coordination and particle size improving the efficacy of NO delivery.
Article Synopsis
- This text reviews the development and applications of MFM-300(Sc), a versatile metal-organic framework (MOF) that has gained traction since its initial introduction.
- It specifically emphasizes the material's capabilities in adsorbing gases, particularly acidic and corrosive types, and its catalytic properties due to its unique Sc-O bond character.
- Additionally, the review explores new research opportunities, including areas like host-guest chemistry and biomedical applications, showcasing the material's potential for future use.
Article Synopsis
- The MOF-type Ni(dobpdc) exhibits high stability and capacity for sulfur dioxide (SO) capture, achieving 4.3 mmol/g at low pressure (0.05 bar) and room temperature (298 K).
- It demonstrates excellent cycling performance, indicating durability over repeated use.
- Fluorescence and time-resolved photoluminescence experiments reveal its effective SO detection capabilities and suggest a possible mechanism for this detection.
Article Synopsis
- Researchers developed easy, HF-free methods to create flexible porous coordination polymers (PCPs) like MIL-53(Cr) and its new variants MIL-53(Cr)-Br and MIL-53(Cr)-NO.
- All three PCPs effectively absorb SO at room temperature and maintain their chemical stability in both dry and wet conditions.
- MIL-53(Cr)-Br displayed significant changes in light emission when exposed to SO, suggesting its potential use in sensing technologies.
Article Synopsis
- Commercial plantations in northern Brazil have faced increased challenges due to the fungal leaf disease known as leaf blight (CLB), primarily affecting local crops.
- A survey in three northeastern plantations identified a diverse range of fungal species responsible for CLB, highlighting the disease's complexity.
- Researchers discovered two new species of fungi, confirmed their pathogenicity, and classified several isolates according to specific naming conventions based on genetic and morphological analyses.
Background: Since the beginning of the COVID-19 pandemic, a great variability of symptoms that affect all organs and systems of the body has been identified in patients with SARS-CoV-2 infection; this symptomatology can sometimes persist over time, giving rise to the so-called long COVID or post-COVID. The aim of this study is to delve into the clinical characterization of these patients, as well as to take into account the influence of factors such as hospitalization, admission to ICU, history of pneumonia, or vaccination status on the persistence of symptoms.
Material And Methods: An observational, descriptive, multicenter, and retrospective study was designed with a series of cases of people who presented long COVID, which includes univariate, bivariate, and multivariate analyses.
The validation of measuring instruments in the field of health is a requirement before they can be used safely and reliably. The action research arm test (ARAT) tool is an instrument validated in numerous countries and languages and for different populations, and its use is widespread. The objective of this research was to determine the psychometric properties of ARAT for a sample composed of post-stroke patients.
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- * A major challenge in using AuNPs is enhancing their sensitivity and selectivity for better sensing methods and multifunctional platforms for drug or gene delivery.
- * The review focuses on recent advancements in AuNPs within the field of biomedicine, emphasizing their roles as biosensors and targeted delivery systems.
Article Synopsis
- - The novel metal-organic framework (MOF) CUK-1, made using Mn(II) and water, effectively captures polar gases like hydrogen oxide (HO), sulfur oxide (SO), and hydrogen sulfide (HS), showcasing its environmentally friendly design.
- - Unlike earlier versions with Co(II) and Mg(II), Mn-CUK-1 exhibits unique temperature-induced structural flexibility due to the twisting of organic linkers, as revealed through single-crystal X-ray diffraction studies.
- - This MOF stands out for having the highest capacity-to-surface area ratio for hydrogen sulfide (HS) among stable MOFs and maintains structural integrity in humid or corrosive conditions, demonstrating versatile behavior based on temperature and the
Background: cognitive impairment is known to be very common in patients with hip fractures, but studies are needed to help understand the relationship between both events. Our goal was to determine the relationship between moderate or severe cognitive impairment and hip fractures during the six months following that episode.
Methods: a retrospective longitudinal study was conducted on a sample of 665 people over 65 years of age.
(1) Background: Hip fracture is a pathology with high mortality, but the lack of a universal adaptation of the factors associated with death makes it difficult to predict risk and implement prevention in this group. This study aimed to identify the factors that determine a higher mortality at six months following hip fracture. (2) Methods: A retrospective longitudinal study, whose study population consisted of patients over 65 years of age.
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- Metal-organic polyhedra (MOPs) can be linked to create porous soft materials that are both processable and permanently porous, but controlling their porosity remains a challenge due to random arrangements in networks.
- * Researchers developed a method to create linked MOP gels with adjustable porosity by introducing negative charges on MOP surfaces, leading to electrostatic repulsion that stabilizes the structures.
- * The study used a rhodium-based MOP (OHRhMOP) with hydroxyl groups that can be modified for controlled interactions with linkers, producing gels with varied porosities when heated.
Article Synopsis
- - There is increasing interest in metal-organic cages (MOCs) as porous materials due to their ability to be processed in solution, which makes them versatile for various applications.
- - The unique molecular structure and surface characteristics of MOCs influence how they interact with each other, allowing researchers to fine-tune the physical properties of the resulting materials.
- - The review emphasizes the potential of surface functionalization of MOCs to create different states of porous materials, and it highlights future opportunities for developing complex materials across multiple length scales.
Article Synopsis
- Researchers investigated two metal-organic frameworks, MIL-53(Al)-TDC and MIL-53(Al)-BDC, for their ability to adsorb sulfur oxides (SO).
- MIL-53(Al)-TDC showed rigidity during SO adsorption, while MIL-53(Al)-BDC displayed flexibility with multiple pore sizes allowing for different adsorption phases.
- Both frameworks demonstrated excellent performance for SO capture, even in humid conditions, suggesting their potential use in SO sensing and storage/transportation applications.
(1) Background: Home confinement and social distancing are two of the main public health measures to curb the spread of SARS-Cov-2, which can have harmful consequences on people's mental health. This systematic review aims to identify the best available scientific evidence on the impact that home confinement and social distancing, derived from the SARS-CoV-2 pandemic, have had on the mental health of the general population in terms of depression, stress and anxiety. (2) Methods: A systematic search was conducted on PubMed, Scopus, Web of Science and ScienceDirect between 2 January 2021 and 7 January 2021, in accordance with the recommendations of the PRISMA Declaration.
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- Research on CAU-10 reveals efficient adsorption of sulfur dioxide (SO) using both experimental and computational methods.
- The study identifies that van der Waals interactions play a crucial role in the adsorption process.
- Findings suggest that CAU-10 is a highly effective material for capturing sulfur dioxide.
Article Synopsis
- The study focused on how the structure of Mg-CUK-1 changes when water (HO) molecules are added, examining the material at various levels of moisture.
- Using Powder X-ray diffraction (PXRD), the researchers measured how the dimensions of the Mg-CUK-1 material changed as more HO was loaded, applying a specific refinement technique to analyze the data.
- They discovered that when one water molecule is trapped in the structure (at around 18% humidity), it creates a bottleneck effect that enhances the material's ability to capture carbon dioxide (CO).
Article Synopsis
- * Chemisorbed sulfur species in MFM-300(Sc) were found to be low-order polysulfides.
- * The similar framework MFM-300(In) facilitates the creation of various polysulfide species, which could lead to innovative uses of MOFs in lithium/sulfur battery technologies.