Clinical pathological significance of iron metabolism with chronic hepatitis C patients.

Serum ferritin levels, and histological liver iron content were determined in 106 patients with chronic hepatitis C (CHC) to find out whether iron status is involved in the pathogenesis of CHC and to study the relationship between sexual differences and the liver function test and liver histology. The serum ferritin index (SFI) as an indicator when both male and female subjects are combined was calculated. SFI significantly correlated with serum aminotransferase levels.