Publications by authors named "Sana Hosny Barakat"
Article Synopsis
- The study investigates the effectiveness and safety of various antibiotic therapies for eradicating Helicobacter pylori (H. pylori) infection in children, focusing on options like triple, sequential, hybrid, concomitant, and ciprofloxacin-based therapies.
- A randomized trial involving 200 children (ages 3-16) revealed that ciprofloxacin-based triple therapy achieved the highest eradication rate at 90%, compared to lower rates for other therapies, with no significant difference in adverse effects.
- The conclusion highlights that ciprofloxacin-based triple therapy is the most effective and safe option for treating H. pylori infection in children, while the other treatment options do not significantly outperform traditional triple therapy.*
Background: The severity of Helicobacter pylori infection is determined by the interplay between bacterial virulence, host genetic and environmental factors. This study aimed to identify interleukin-1 beta (IL-1β) and interleukin receptor antagonist (IL-1RN) gene polymorphisms and their associations with H. pylori infection, and severity of chronic gastritis in Egyptian children.
View Article and Find Full Text PDFObjectives: To evaluate the effect of bovine colostrum (BC) on the treatment of children with acute diarrhea attending the outpatient clinic.
Methods: This double-blind randomized controlled trial was conducted on 160 children with diarrhea; 80 cases were randomly treated with BC group and 80 cases randomly received placebo (placebo group). All cases were investigated for bacterial causes of diarrhea (Salmonella spp, Shigella spp, diarrheagenic E.