The TP63 Gene Polymorphism rs17506395 is Associated with Early Breast Cancer in Cameroon.

Background: Breast cancer (BC) is a leading female cancer worldwide and cause of cancer-related death, especially in developing countries. Genetic predispositions to BC development in African population is poorly studied, and meanwhile the SNP rs17506395 in TP63 gene locus has been associated with the development of breast cancer in Asian women, no investigation has been undertaken within African population. We investigated the impact of this polymorphism in a representative African population.

Bacteriological assessment of the hospital environment in two referral hospitals in Yaoundé-Cameroon.

Introduction: Many studies still show significant numbers of surgical patients contracting nosocomial infections each year globally with high morbidity and mortality. The aim of this study was to identify potential bacteria reservoirs that may be responsible for nosocomial infection in surgical services in the Yaoundé University Teaching Hospital (YUTH) and the Central Hospital Yaoundé (CHY).

Methods: A cross sectional descriptive study was conducted from June to August 2012.

[Synovial Osteochondromatosis At The Rheumatology Unit Of The Yaounde Central Hospital].

Synovial osteochondromatosis is a disease characterized by a benign metaplastic cartilaginous proliferation. There are very few studies on synovial osteochondromatosis in Sub Saharan Africa. We report on 10 observations.

Patients characteristics and outcome of 518 arteriovenous fistulas for hemodialysis in a sub-Saharan African setting.

Background: To present the particular aspects of arteriovenous fistula (AVF) for hemodialysis in sub-Saharan Africa in terms of patients' characteristics, patency and complication rates, as well as factors influencing them.

Methods: From November 2002 to November 2009, 518 fistulas were constructed on adults. Demographic data, patency, and complications were analyzed.

Meckel's diverticulum: a case report from the University Hospital Center Yaoundé, Cameroon.

To the best of our knowledge there is no reported case of Meckel's diverticulum (MD) in Cameroon. The prevalence of MD in the general population is 2-3 %. The aim of this paper is to recapitulate the role of this pathology in acute abdomens and abdominal pain of uncertain aetiology in young patients and to review the medical literature.

Management of neural tube defects in a Sub-Saharan African country: the situation in Yaounde, Cameroon.

Background: Neural tube defect is a serious disabling but preventable congenital malformation with an incidence of 1.99 per 1000 births in Yaounde [A.K.

Determination of chemical composition of gall bladder stones: basis for treatment strategies in patients from Yaounde, Cameroon.

Aim: Gallstone disease is increasing in sub-saharan Africa (SSA). In the west, the majority of stones can be dissolved with bile salts, since the major component is cholesterol. This medical therapy is expensive and not readily accessible to poor populations of SSA.