The role of plasmids in carbapenem resistant E. coli in Alameda County, California.

Background: Antimicrobial resistant infections continue to be a leading global public health crisis. Mobile genetic elements, such as plasmids, have been shown to play a major role in the dissemination of antimicrobial resistance (AMR) genes. Despite its ongoing threat to human health, surveillance of AMR in the United States is often limited to phenotypic resistance.

Clonal Lineages and Virulence Factors of Carbapenem Resistant in Alameda County, California, 2017-2019.

The prevalence of carbapenem-resistant (CRE) has been increasing since the year 2000 and is considered a serious public health threat according to the Centers for Disease Control and Prevention. Limited studies have genotyped Carbapenem-resistant using whole genome sequencing to characterize the most common lineages and resistance and virulence genes. The aim of this study was to characterize sequence data from carbapenem-resistant isolates ( = 82) collected longitudinally by the Alameda County Public Health Laboratory (ACPHL) between 2017 and 2019.