Lipidomics-Based Comparison of Molecular Compositions of Green, Yellow, and Red Bell Peppers.

Identifying and annotating the molecular composition of individual foods will improve scientific understanding of how foods impact human health and how much variation exists in the molecular composition of foods of the same species. The complexity of this task includes distinct varieties and variations in natural occurring pigments of foods. Lipidomics, a sub-field of metabolomics, has emerged as an effective tool to help decipher the molecular composition of foods.

Targeting in Pediatric and Adult Cancers.

The deregulation of the family of oncogenes, including , and occurs in many types of cancers, and is frequently associated with a poor prognosis. The majority of functional studies have focused on due to its broad expression profile in human cancers. The existence of highly conserved functional domains between and suggests that participates in similar activities.

Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2.

Although the insulin receptor substrate (IRS) proteins IRS1 and IRS2 share considerable homology and activate common signaling pathways, their contributions to breast cancer are distinct. IRS1 has been implicated in the proliferation and survival of breast tumor cells. In contrast, IRS2 facilitates glycolysis, invasion, and metastasis.