Publications by authors named "Samuel Paul Isaac"

Physiotherapy has significantly evolved since its inception in the late 19th century, expanding into various specializations such as sports, neurology, and wound care. Its primary goal is to restore or enhance bodily functions through therapeutic interventions, aiding in conditions ranging from injuries to chronic pain. Tissue recovery, which involves repair and regeneration, is a critical aspect of physiotherapy.

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Bolivian hemorrhagic fever (BHF) caused by Machupo virus (MACV) is a New World arenavirus having a reported mortality rate of 25-35%. The BHF starts with fever, followed by headache, and nausea which rapidly progresses to severe hemorrhagic phase within 7 days of disease onset. One of the key promoters for MACV viral entry into the cell followed by viral propagation is performed by the viral glycoprotein (GPC).

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The COVID-19 pandemic caused by SARS-CoV-2 virus has created a global damage and has exposed the vulnerable side of scientific research towards novel diseases. The intensity of the pandemic is huge, with mortality rates of more than 6 million people worldwide in a span of 2 years. Considering the gravity of the situation, scientists all across the world are continuously attempting to create successful therapeutic solutions to combat the virus.

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