Publications by authors named "Samuel Oliveira de Afonseca"
Background: Heart failure is a severe complication associated with doxorubicin (DOX) use. Strain, assessed by two-dimensional speckle tracking (2D-STE), has been shown to be useful in identifying subclinical ventricular dysfunction.
Objectives: a) To investigate the role of strain in the identification of subclinical ventricular dysfunction in patients who used DOX; b) to investigate determinants of strain response in these patients.
CONTEXT AND OBJECTIVE Oxaliplatin is one of the chemotherapy regimens most used for treating colorectal cancer. One of the main limitations to its use is induction of peripheral neuropathy. Previous studies have shown that vitamin E can reduce the incidence of peripheral neuropathy by 50%.
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- Chemotherapy can make patients feel really sick and sometimes even throw up, which is called chemotherapy-induced nausea and vomiting (CINV).
- A study tested a medicine called gabapentin to see if it could help stop this sickness during treatment, comparing it to a fake pill (placebo).
- The results showed that gabapentin helped more patients feel better and avoid nausea and vomiting, especially after the first days of chemotherapy, without causing extra side effects.