Immunoinformatics analysis to design novel epitope based vaccine candidate targeting the glycoprotein and nucleoprotein of Lassa mammarenavirus (LASMV) using strains from Nigeria.

Lassa mammarenavirus (LASMV) is responsible for a specific type of acute viral hemorrhagic fever known as Lassa fever. Lack of effective treatments and counter-measures against the virus has resulted in a high mortality rate in its endemic regions. Therefore, in this study, a novel epitope-based vaccine has been designed using the methods of immunoinformatics targeting the glycoprotein and nucleoprotein of the virus.

A Crisis within a Crisis: COVID-19 and Hunger in African Children.

The WHO recently expressed concern at the potential impact of COVID-19 on hunger, which is likely to exacerbate the already considerable burden of malnutrition of Africa. The impact of the disease is expected to be greater among those grappling with malnutrition, whereas widespread hunger and malnutrition will likely increase because of movement restrictions. COVID-19 is unfolding in Africa against a backdrop of worrying levels of hunger and undernourishment which could worsen as the virus threatens livelihoods and household economies.