Preclinical antidiabetic and antioxidant effects of (benth.) harms in streptozotocin-induced diabetic nephropathy.

Objectives: This study investigated the antidiabetic effects of the methanolic extract of (MEEA) stem bark on streptozotocin (STZ)-induced diabetic nephropathy (DN) in Wistar rats.

Methods: The enzyme (α-amylase) inhibitory activity of MEEA was measured using a standard procedure. Diabetic rats with fasting blood glucose above 250 mg/dL were considered diabetic and were divided into the following groups: control (distilled water-treated), diabetic-control, diabetic metformin (100 mg/kg), diabetes + MEEA (150 mg/kg), and diabetes + MEEA (300 mg/kg) via oral gavage once daily for 14 days.

Spilanthes filicaulis (Schumach. & Thonn.) C. D Adam leaf extract prevents assault of streptozotocin on liver cells via inhibition of oxidative stress and activation of the NrF2/Keap1, PPARγ, and PTP1B signaling pathways.

Background: Spilanthes filicaulis (Schumach. & Thonn.) C.

Sole and Combined Application of Biodigestate, N, P, and K Fertilizers: Impacts on Soil Chemical Properties and Maize Performance.

The fertilizing effects of biodigestate produced from biogas plants on crop and soil productivity are very scarce. Hence, a field study was conducted in 2022 at the Teaching and Research Farm of Bowen University, Iwo, Osun State, Nigeria. The study evaluated the effects of biodigestate fertilizer, applied alone or in combination with urea, single superphosphate, or muriate of potash fertilizers at low (N, K, and P) and high (N, P, and K) rates on soil chemical properties, growth, and yield of maize ( (L.

Draft genome sequence of multi-drug resistant subsp. isolated from a teaching hospital wastewater in South West, Nigeria.

This broadcast is about the whole genome sequence of subsp. (ST 1422) isolated from a teaching hospital wastewater in South West, Nigeria, in May 2022. This data set compiles information on the DNA size (5,332,183 bp) and GC content (57.

Nutritional, functional, and bioactive properties of african underutilized legumes.

Globally, legumes are vital constituents of diet and perform critical roles in maintaining well-being owing to the dense nutritional contents and functional properties of their seeds. While much emphasis has been placed on the major grain legumes over the years, the neglected and underutilized legumes (NULs) are gaining significant recognition as probable crops to alleviate malnutrition and give a boost to food security in Africa. Consumption of these underutilized legumes has been associated with several health-promoting benefits and can be utilized as functional foods due to their rich dietary fibers, vitamins, polyunsaturated fatty acids (PUFAs), proteins/essential amino acids, micro-nutrients, and bioactive compounds.

Organic and in-organic fertilizers effects on the performance of tomato (Solanum lycopersicum) and cucumber (Cucumis sativus) grown on soilless medium.

The effects of organic fertilizers, based on Tithonia diversifolia, and in-organic fertilizers, based on hydroponics fertilizer, were evaluated on the performance, leaves, and fruit mineral concentrations of tomato (Solanum lycopersicum) and cucumber (Cucumis sativus) plants grown under soilless medium in a screen house. The treatments comprised six levels of liquid organic fertilizer (5, 15, 25, 35, 45, 55 mL), in-organic fertilizer, and a control. Both organic and in-organic fertilizers increased the growth, yield, leaf nutrient concentration, and the mineral contents of tomato and cucumber fruits in comparison with the control.

Co-occurrence of Species During Fermentation of African Indigenous Foods: Impact on Food Safety and Shelf-Life Extension.

The benefits derived from fermented foods and beverages have placed great value on their acceptability worldwide. Food fermentation technologies have been employed for thousands of years and are considered essential processes for the production and preservation of foods, with the critical roles played by the autochthonous fermenting food-grade microorganisms in ensuring food security and safety, increased shelf life, and enhanced livelihoods of many people in Africa, particularly the marginalized and vulnerable groups. Many indigenous fermented foods and beverages of Africa are of plant origin.

Performance and quality attributes of okra (Abelmoschus esculentus (L.) Moench) fruits grown under soil applied Zn-fertilizer, green biomass and poultry manure.

Field experiments were carried out in 2018 and 2019 cropping seasons at Landmark University Teaching and Research farm, Omu-Aran Kwara state, Nigeria, to determine the effect of soil applied Zn-fertilizer, Tithonia diversifolia (Ti), Chromolaena odorata (Ch) and poultry manure (PM) on the performance, yield, minerals and vitamins composition of okra fruits. Treatments were combined and tested as follows:-Control (T), Control + 10 kg ha Zn (T), 5 t ha Ti + 5 t ha PM (T), 5 t ha Ch + 5 t ha PM (T), 5 t ha Ch + 5 t ha Ti (T), 10 t ha Ti + 0 kg ha Zn (T), 10 t ha Ti + 10 kg ha Zn (T), 10 t ha Ch + 0 kg ha Zn (T), 10 t ha Ch + 10 kg ha Zn (T), 10 t ha PM + 0 kg ha Zn (T), and 10 t ha PM + 10 kg ha Zn (T). The experiment was laid out in a randomized complete block design with four repetitions.

Malaria coinfection with Neglected Tropical Diseases (NTDs) in children at Internally Displaced Persons (IDP) camp in Benin City, Nigeria.

Malaria and Neglected Tropical Diseases (NTDs) are highly endemic in poorer countries of the world. The research investigated the prevalence of parasitic infections among children in Internally Displaced Persons (IDP) camp in Benin City. Faecal, urine and blood specimen were collected from 184 children (100 males and 84 females) aged 6-15.

Energy generation from anaerobic co-digestion of food waste, cow dung and piggery dung.

The study investigated bioenergy generation from anaerobic co-digestion of food wastes (FW), cow dung (CD) and piggery dung (PD). The physicochemical parameters of the substrates were determined before and after digestion following standard procedures after mechanical pretreatment. Throughout the study, pH remained slightly alkaline while temperature varied between 26 and 32 °C.

Corrigendum to "Antidiabetic, antioxidant and antimicrobial activities of extracts of leaves" [Heliyon 5 (8) (August 2019) e02275].

[This corrects the article DOI: 10.1016/j.heliyon.

Antidiabetic, antioxidant and antimicrobial activities of extracts of leaves.

Aims: Plant extracts have long been used for the ethnomedical treatment of diabetes, microbial infections and as a source of antioxidant. This study was aimed at investigating the antidiabetic, antioxidant, and antimicrobial activities of the n-hexane and ethyl acetate extract of leaves (TBL) as associated with the ethnobotanical knowledge of the local people of Nigeria.

Main Methods: The phytochemical composition of the n-hexane and ethyl acetate extract of the leaves of were determined following standard procedures in literature, and it's inhibitory activities against α-glucosidase enzyme.