Co-exposure to Aluminium and Cadmium Mediates Postpartum Maternal Variation in Brain Architecture and Behaviour of Mice; Involvement of Oxido-nitrergic and Cholinergic Mechanisms : Postpartum effects of Aluminium and Cadmium co-exposure in pregnancy.

Most research has not been done on the possible relationship between pregnant women's cross-metal exposures and postpartum neuroendocrine functions. The purpose of this study was to look into how co-exposure to aluminium chloride (AlCl) and cadmium chloride (CdCl) affected the neuroendocrine and neurometabolic changes in postpartum mice. A total of 24 adult pregnant female mice were used for the study.

Hepatocellular degeneration in mice co-exposed to in-utero aluminium and cadmium: Implication of a disordered antioxidant and energy homeostatic response in the liver.

The current study comprised four groups of pregnant animals viz; Control (CTR) received 10 ml/kg of normal saline, Al:10 mg/kg of AlCl, Cd: 1.5 mg/Kg of CdCl Al+Cd; 10 mg/kg of AlCl and 1.5 mg/Kg of CdCl.

Prenatal double-hit with aluminium and cadmium mediate testicular atrophy and hypothalamic hypoplasia: the role of oxido-nitrergic stress and endocrine perturbations.

There is limited experimental evidence on the biochemical consequences of aluminium (Al) and cadmium (Cd) co-exposures during pregnancy and postnatal life.This study investigated the impacts of perinatal Al chloride (AlCl) and Cd chloride (CdCl) co-exposures on neuroendocrine functions in mice offspring during postnatal life. The study comprised of four pregnant experimental groups.

Exposure of African Catfish (Clarias gariepinus) to Lead and Zinc Modulates Membrane-Bound Transport Protein: A Plausible Effect on Na/K-ATPase Activity.

The contamination of the aquatic ecosystem beyond tolerable limits may pose serious health challenges to its components. This study evaluated the toxic effects of a binary mixture of lead (Pb) and zinc (Zn) compounds on the activity of Na/K-ATPase in tissues of Clarias gariepinus in a controlled aquatic system. The study employed Box-Behnken Design (BBD) with 17 runs in which Pb and Zn concentrations were considered process variables in a time-dependent fashion.

Influence of farmyard manure on some morphological and biochemical parameters of cowpea (Vigna unguiculata) seedling grown in cadmium-treated soil.

The present study aims to assess the effects of the two kinds of farmyard manure (poultry and pig manures) as amendments for soil on cadmium (Cd) toxicity in plants using cowpea seedlings as plant model. Cd toxicity was evaluated by assessing the effect of the metal on the growth rate and antioxidant status as well as the ability of the plant to metabolise xenobiotic. There was a significantly (p < 0.

Effect of a controlled food-chain mediated exposure to cadmium and arsenic on oxidative enzymes in the tissues of rats.

Objective: The present study aims to investigate the effect of cadmium and arsenic through a controlled food chain on the activities of some oxidative enzymes (Sulphite oxidase SO, Aldehyde oxidase AO, Monoamine oxidase MO and Xanthine oxidase, XO) in the liver, kidney, testes, heart and brain of rats.

Materials And Methods: Fish (the first trophic level) were exposed to both metals (singly and in mixture) using cadmium chloride (CdCl) as the source of cadmium and arsenic trioxide (ASO) as the source of arsenic at a concentration of 0.4 mg of metals/100 ml of water for 1 month and then sacrificed.

Alteration in the activity of oxidative enzymes in the tissues of male Wistar albino rats exposed to cadmium.

Objective: The objective of the present study was to investigate the effect of cadmium (Cd) on the activities of some oxidative enzymes [viz Aldehyde oxidase, AO (E.C. 1.

Comparative effect of water and food-chain mediated cadmium exposure in rats.

This study sets out to compare the absorption and toxicity of Cadmium (Cd) administered via the food-chain and inorganic Cd administered in drinking water after 1 and 3 months exposure using rats as animal model. The food-chain was mimicked by exposing rats to diet containing Cd pre-exposed fish. The uptake of Cd by the rats after both mode of exposure was calculated by summing up the Cd burden in the liver and kidneys and was expressed in terms of % intake.

Bioaccumulation of cadmium and its biochemical effect on selected tissues of the catfish (Clarias gariepinus).

The present study examines the pattern of accumulation of cadmium (Cd) and its biochemical effects on selected tissues of a variety of African catfish (Clarias gariepinus), after exposure to various doses of Cd. The results obtained indicate that at the end of 21 days of exposure, the total tissue organ cadmium concentration followed the pattern kidney > gill > liver > muscle for each of the exposure concentrations. The levels of Cd in these organs were higher than those in ambient water.

A comparative study on the archives of xanthine oxidase and aldehyde oxidase in different fish species from two rivers in the Western Niger-Delta.

Glycaemia, a classical indicator of stress, xanthine oxidase and aldehyde oxidase which are involved in phase I detoxication were investigated in two different fish species from two rivers with different pollution levels in the Western Niger-Delta. Four sampling zones covering the entire lengths of Warri and Ethiope Rivers respectively were used in this study. For each species of fish five were obtained from a sampling zone in a river.

Increased superoxide dismutase and Na+, K+-ATPase activities in aortic strips from potassium-adapted rats: implication for altered vascular reactivity.

The contributions of superoxide dismutase (SOD) and Na(+), K(+)-ATPase to the altered vascular reactivity in potassium-adapted rats were investigated to test the hypothesis that smooth muscle hyperpolarisation may be involved. Isometric contractions to noradrenaline (NA), 5-hydroxytryptamine (5-HT), and relaxations to acetylcholine (ACh), levcromakalim (LEV) and sodium nitroprusside (SNP), were measured in aortic rings from potassium-adapted rats. Pieces of the aortae were also excised from the animals and assayed for SOD and Na(+), K(+)-ATPase.