Favourable outcomes for childhood acute lymphoblastic leukaemia in an isolated setting: The Tasmanian experience.

Background: Tasmania is a large, relatively isolated island located south of mainland Australia with limited tertiary level paediatric oncology services.

Aims: To benchmark regional outcomes for childhood acute lymphoblastic leukaemia (ALL) against published international standards.

Methods: We undertook a retrospective cohort study, analysing the clinical characteristics and health outcomes of all children diagnosed with and treated for ALL in Tasmania, Australia between 2006 and 2015.

Skeletal Muscle Microvascular-Linked Improvements in Glycemic Control From Resistance Training in Individuals With Type 2 Diabetes.

Objective: Insulin increases glucose disposal in part by enhancing microvascular blood flow (MBF) and substrate delivery to myocytes. Insulin's microvascular action is impaired with insulin resistance and type 2 diabetes. Resistance training (RT) improves glycemic control and insulin sensitivity, but whether this improvement is linked to augmented skeletal muscle microvascular responses in type 2 diabetes is unknown.