Publications by authors named "Samuel Governor"
Background: Survival differences between left-sided colon cancer (LSCC) and right-sided colon cancer (RSCC) has been previously reported with mixed results, with various study periods not accounting for other causes of mortality.
Purpose: We sought to assess the trends in colon cancer cause- specific survival (CSS) and overall survival (OS) based on sidedness.
Method: Fine-Gray competing risk and Cox models were used to analyze Surveillance, Epidemiology, and End Results (SEER) population-based cohort from 1975 to 2019.
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the coronavirus 19 (COVID-19) pandemic have had a lasting impact on the care of cancer patients. The impact on patients with gastrointestinal (GI) malignancies remains incompletely understood. We aimed to assess the impact of COVID-19 on mortality, length of stay (LOS), and cost of care among patients with GI malignancies, and identify differences in outcomes based on primary tumor site.
View Article and Find Full Text PDFObjective: To assess the risk of select safety outcomes including endometrial cancer, endometrial hyperplasia, and breast cancer among women using conjugated estrogens/bazedoxifene (CE/BZA) as compared with estrogen/progestin combination hormone therapy (EP).
Methods: We conducted a new-user cohort study in five US healthcare claims databases representing more than 92 million women. We included CE/BZA or EP new users from May 1, 2014, to August 30, 2019.
Background: 25% of all breast cancer patients have HER-2 overexpression. Breast Cancer patients with HER-2 overexpression are typically treated with HER-2 inhibitors such as Trastuzumab. Trastuzumab is known to cause a decrease in left ventricular ejection fraction.
View Article and Find Full Text PDFArticle Synopsis
- Colorectal cancer (CRC) sidedness, with left-sided CRC linked to better survival rates than right-sided CRC (RsCC), is influenced by factors like obesity, race, age, and sex.
- A study analyzed data from nearly 25,000 CRC patients, revealing 13.6% were overweight and 49.9% were obese, predominantly non-Hispanic Whites, while overweight and obese individuals had a higher likelihood of developing RsCC.
- The findings highlight that obesity raises the risk of RsCC, particularly emphasizing significant racial disparities in CRC outcomes among obese patients.
Article Synopsis
- Gastrointestinal extrapulmonary small cell carcinoma (GI EPSCCa) is a rare and aggressive type of cancer, and factors influencing survival, like the site of the primary tumor, are still being studied.
- Data from the SEER program (2000-2018) showed that most patients had tumors in the colorectum, esophagus, and pancreas, with notable racial differences in tumor locations but no differences in overall survival among races.
- The study found that different tumor sites affect patient prognosis, with some treatments like surgery and therapies after 2006 leading to better outcomes, though the overall survival rates for GI EPSCCa patients remain poor, highlighting the need for further research.
Treatment for pulmonary arterial hypertension (PAH) has evolved over the past decade, including approval of new medications and growing evidence to support earlier use of combination therapy. Despite these changes, few studies have assessed real-world treatment patterns, healthcare resource utilization (HCRU), and costs among people with PAH using recent data. We conducted a retrospective cohort study using administrative claims from the HealthCore Integrated Research Database®.
View Article and Find Full Text PDFAnnually, about 16,500 HPV-associated cancers occur in the US among men. Data regarding HPV vaccine uptake among men based on nativity status (i.e.
View Article and Find Full Text PDFObjective: The purpose of our study is to develop a mental workload scale for physicians in China and assess the scale's reliability and validity.
Design: The instrument was developed over three phases involving 396 physicians from different tiers of comprehensive public hospitals in China. In the first phase, an initial item pool was developed through a systematic literature review.
Background: The proliferation of mobile health apps has greatly changed the way society accesses the health care industry. However, despite the widespread use of mobile health apps by patients in China, there has been little research that evaluates the effect of mobile health apps on patient experience during hospital visits.
Objective: The purpose of our study was to examine whether the use of mobile health apps improves patient experience and to find out the difference in patient experience between users and nonusers and the characteristics associated with the users of these apps.