Publications by authors named "Samuel G Olukole"
Article Synopsis
- - This study explored how the presence of neuronal and glial cell markers changes in cane rats of different ages by using specific staining techniques on their testes and epididymides.
- - Researchers analyzed 32 male cane rats across four age groups, assessing structures in the testes and epididymis after anesthetizing the animals and applying histochemical methods.
- - Findings revealed that both neuronal and glial cell expressions increased with age, indicating a potential link between these variations and heightened reproductive activity in cane rats.
Age-Related Changes in the Testicular Morphophysiology of the Cane Rat .
J Microsc Ultrastruct
July 2021
Article Synopsis
- - This study examined how the testicular structure and function of cane rats change with age by analyzing histology, histochemistry, and hormone levels across different age groups: prepubertal, pubertal, adult, and aged.
- - Results indicated that testosterone levels increased significantly from prepubertal to adult stages but plateaued in aged rats, while follicle-stimulating hormone levels decreased significantly in younger age groups but not between adult and aged rats.
- - Histological findings showed significant differences in testicular characteristics: prepubertal rats had fewer interstitial cells and incomplete sperm cell series, while older rats exhibited increased testicular staining intensity and larger seminiferous tubules, peaking in the adult stage, thus indicating that reproductive
Objectives: Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on the BPA-induced testicular oxidative stress in adult male Wistar rats using serum hormone analysis, histopathology, and biochemical assays.
Methods: Adult male rats were divided into four groups (n=10) including control (0.
Article Synopsis
- * Pregnant Wistar rats were divided into groups, some receiving BPA alone at varying doses and others receiving BPA with melatonin to assess its protective effects.
- * Results showed BPA exposure led to reduced body weight, hormonal imbalances, oxidative stress in the testis, and damage to reproductive tissues, while MLT co-treatment appeared to mitigate these adverse effects.
Article Synopsis
- * Male rats were divided into four groups: a control group, a group receiving MLT only, a group exposed to BPA, and a group exposed to both BPA and MLT.
- * Results showed that BPA led to significant increases in hormonal levels and various signs of toxicity in the adrenal glands, but the combined treatment with MLT helped reduce these harmful effects, indicating MLT's potential antioxidant benefits.
Bisphenol A (BPA) is a small molecular weight endocrine disrupting chemical (EDC) that is used in the production of plastics with deleterious effects on various body systems while gallic acid (GA) is a known antioxidant capable of ameliorating EDC-induced perturbations. In this study, adult male rats (180 ± 5 g) were divided into four groups of eight rats each: Group A (Control rats): 0.2 ml of corn oil; Group B (GA-treated rats): 20 mg/kg/day GA (dissolved in distilled water); Group C (BPA-treated rats): 10 mg/kg/day BPA suspended in 0.
View Article and Find Full Text PDFArticle Synopsis
- Bisphenol A (BPA) is identified as an endocrine disrupting chemical that negatively affects the reproductive organs, while melatonin (ML) serves as a protective antioxidant against these effects.
- In a study involving adult male Wistar rats divided into four groups, those treated with BPA exhibited increased prostatic index and altered hormone levels, while concurrent administration of ML helped improve these adverse conditions.
- The study concludes that low doses of melatonin can mitigate the harmful effects of BPA on prostate health, as shown by improved hormonal balance and reduced structural damage in the prostate gland of rats.
Article Synopsis
- Aloe vera is a commonly used herb that was tested for its effects on the semen quality of West African Dwarf bucks.
- In the study, twelve bucks were divided into two groups and treated with different concentrations of Aloe vera extract over 14 days, with semen samples collected before and after treatment.
- The results showed that Aloe vera significantly decreased sperm concentration, motility, and livability while increasing sperm abnormalities, indicating it could negatively impact male fertility and breeding.
The report of the occurrence of additional renal arteries in domestic animals is rare in the literature. We report a case of an additional renal artery in the left kidney found in a Red Sokoto goat cadaver. The additional renal artery originated from the abdominal aorta 3.
View Article and Find Full Text PDFGonadal and extragonadal sperm reserves were determined in twenty sexually matured domesticated African greater cane rats. Mean (+/-SD) sperm numbers in testes and epididymides were 150.40+/-12.
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