Publications by authors named "Samuel D Lee"

Cognitive ability tests are widely used in employee selection contexts, but large race and ethnic subgroup mean differences in test scores represent a major drawback to their use. We examine the potential for an item-level procedure to reduce these test score mean differences. In three data sets, differing proportions of cognitive ability test items with higher levels of difficulty or subgroup mean differences were removed from the tests.

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The neocortex is disproportionately expanded in human compared with mouse, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons that selectively make connections within the neocortex and with other telencephalic structures. Single-cell transcriptomic analyses of human and mouse neocortex show an increased diversity of glutamatergic neuron types in supragranular layers in human neocortex and pronounced gradients as a function of cortical depth. Here, to probe the functional and anatomical correlates of this transcriptomic diversity, we developed a robust platform combining patch clamp recording, biocytin staining and single-cell RNA-sequencing (Patch-seq) to examine neurosurgically resected human tissues.

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Neurons are frequently classified into distinct types on the basis of structural, physiological, or genetic attributes. To better constrain the definition of neuronal cell types, we characterized the transcriptomes and intrinsic physiological properties of over 4,200 mouse visual cortical GABAergic interneurons and reconstructed the local morphologies of 517 of those neurons. We find that most transcriptomic types (t-types) occupy specific laminar positions within visual cortex, and, for most types, the cells mapping to a t-type exhibit consistent electrophysiological and morphological properties.

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Over a century of research has focused on the relationship between student characteristics and academic dishonesty. Here we conduct a meta-analysis of this extensive literature across three broad domains: personality, academic attitudes, and historical information including demographic and prior accomplishments. After analyzing correlations from over 27,000 participants across 75 samples, several relationships stand out.

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