Publications by authors named "Samuel C Troughton"
Acta Biomater
August 2024
Article Synopsis
- Regenerative cardiac patches can enhance heart function by providing support and reducing stress on the ventricular wall, but integrating these scaffolds into the heart remains difficult due to biomechanical challenges.
- This study uses a Langendorff ex-vivo model to examine how well engineered scaffolds mimic natural heart tissue under stress, utilizing advanced imaging techniques to measure deformation.
- Results show that scaffolds with aligned pores secured with sutures most effectively replicate natural heart tissue behavior, highlighting the importance of scaffold design for improving cardiac tissue engineering outcomes.
