Titration of pulmonary arterial hypertension therapeutics: Experience-based recommendations.

The availability of new medications has improved exercise capacity, enhanced quality of life, and extended time to clinical worsening in patients with pulmonary arterial hypertension (PAH). For many of these medications, careful individualized dose titration is required to maximize therapeutic effectiveness while minimizing side effects. In addition, specific routes of administration, including intravenous (IV), subcutaneous (SC), and inhaled administration may present additional challenges for patients and healthcare providers.

A Case of Ocular Syphilis in a 36-Year-Old HIV-Positive Male.

The incidence of syphilis in the United States has increased markedly over the last decade, particularly among men who have sex with men (MSM). Although uncommon, ocular involvement is a potentially devastating clinical manifestation of syphilis. Human immunodeficiency virus (HIV) infection appears to increase the risk of ocular syphilis.

Normal anatomic relationships in prepubescent female external genitalia.

Objective: Female congenital abnormalities and concomitant ambiguous genitalia constitute the primary reason for female genital reconstruction, however, objective data describing normal female anatomy is lacking. The aim of this study is to describe the normal anatomical relationships and size of the external genital structures in prepubescent females.

Materials And Methods: Data were collected prospectively from consecutive Tanner stage 1 females undergoing surgery unrelated to the genitalia.

Newborn length predicts early infant linear growth retardation and disproportionately high weight gain in a low-income population.

Background: Stunting is prevalent by the age of 6 months in the indigenous population of the Western Highlands of Guatemala.

Aim: The objective of this study was to determine the time course and predictors of linear growth failure and weight-for-age in early infancy.

Study Design And Subjects: One hundred and forty eight term newborns had measurements of length and weight in their homes, repeated at 3 and 6 months.

Salmonella spinal infection: a rare case in a patient with advanced AIDS.

We present an unusual case of nontyphoidal Salmonella causing an epidural abscess and vertebral osteomyelitis in a severely immunocompromised patient with AIDS as well as a review of the literature. Salmonella vertebral osteomyelitis is exceptionally rare, and this is the first case report in a patient with AIDS.