Publications by authors named "Samuel Akinyele"
Ethnopharmacological Relevance: Locally, among the Yoruba speaking people of South Western, Nigeria, the bulb of Crinum jagus (CJ), known as "ogede odo" is used to treat malaria and as an anthelmintic among other uses.
Aims Of This Study: Study aimed at identifying the purified active fractions and constituents of this fraction in an antiplasmodial activity-guided process.
Materials And Methods: Antiplasmodial activity-guided fractionation of the bulb and leaf extracts of CJ was investigated against chloroquine-sensitive (NK 65) Plasmodium berghei using 4-day suppressive and prophylactic methods.
Objective: To evaluate the use of tocilizumab in a community hospital setting for critically ill patients with severe COVID-19.
Design: A retrospective case series.
Setting: Five community hospitals within 1 urban health system.
Purpose: Results of a study to determine the utility of combining laboratory values and clinical probability scores to improve the detection of heparin-induced thrombocytopenia (HIT) are reported.
Methods: In a retrospective, single-site, chart review-based investigation, 156 cases in which patients with suspected HIT had positive results on a widely used diagnostic test (the anti-heparin/platelet factor 4, or anti-PF4, assay) were identified; in all cases, the blood specimens had been sent to a reference laboratory for confirmation of HIT via serotonin release assay (SRA). After investigator scoring of the clinical probability of HIT in each case by the 4T's method, a multiple logistic regression model was used to evaluate the combined effect of 4T's scores and anti-PF4 assay values in predicting SRA results.