Publications by authors named "Samudio M"

Introduction And Importance: Sternutation is, by definition, a situation that increases abdominal pressure. However, it has not been clearly linked to protrusion of abdominal content through weaknesses in the abdominal boundaries.

Case Presentation: Here we present a case report in which the only trigger factor found for an abdominal content protrusion was a sternutation episode.

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Melanotic schwannoma (MS) is a rare and infrequent subtype of schwannoma characterized by cytoplasmic deposits of melanosomes (melanin). Unlike the other schwannomas, it could have malignant transformation. Due to distinctive characteristics and atypical behavior from classic schwannomas subtypes, MS were renamed and reclassified as "melanocytic malignant neural sheath tumor" in the 5th ed.

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Article Synopsis
  • Rabies virus (RABV) poses a risk to cattle in Paraguay, leading to a need for effective detection methods.
  • Four techniques were evaluated: fluorescent antibody test (FAT), rapid detection test (RDT), reverse-transcription PCR (RT-PCR), and histological examination in samples from 49 cattle.
  • The RDT showed perfect sensitivity and specificity, matching FAT exactly, while RT-PCR also demonstrated good agreement but slightly lower sensitivity, highlighting RDT as a reliable and accessible detection tool for rabies in cattle.
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Background: The health crisis due to Covid-19 led to the search for therapeutics that could improve the evolution of the disease. Remdesivir, an antiviral that interferes with viral replication, was one of the first to be used for the treatment of this pathology.

Objective: To determine clinical course and mortality of patients with severe SARS-CoV-2 pneumonia treated with remdesivir, in comparison of those who didn't receive the medication.

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remains a major cause of mortality and morbidity worldwide in children <5 years of age, even with advances in vaccination programmes. Reviewing and reporting trends in the distribution of pneumococcal serotypes and antimicrobial resistance in Paraguay will be useful for decision-making in public health..

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Background: COVID-19, caused by the severe acute respiratory syndrome virus type-2 (SARS-CoV-2), was declared a pandemic in March 2020. Seroprevalence studies are useful to estimate the proportion of the population previously infected, quantify the magnitude of transmission, estimate the fatality rate, evaluate the effect of interventions, and estimate the degree of immunity of the population.

Aim: To determine the extension of the infection and the cumulative incidence of age-specific infection, determined by seropositivity in the population of the sanitary regions of Asunción and the Central Department of Paraguay.

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Purpose: To analyze antibiotic resistance and genetic profile of conjunctival bacteria flora before and after cataract surgery with the focus on coagulase-negative staphylococci (CNS) during cataract surgery and discuss the implications of this colonization as a potential risk of acquiring endophthalmitis.

Methods: After approval of the institutional review board and informed consent from patients had been obtained, conjunctival swabs for culture from 59 patients undergoing cataract surgery were taken of the fellow eye at baseline (C0) and from the eye to be operated before (T0) and after (T1) irrigation with povine-iodine 5%, and at the end of surgery (T2). Genes responsible for virulence (mecA, ica and atlE) and antibiotic profile were determined; strain clonality of persistent colonizing Staphylococcus epidermidis strains was established by the Multi-locus sequence typing (MLST).

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Article Synopsis
  • A 76-year-old woman in Asunción developed keratitis caused by the rare bacterium M. abscessus, despite having no eye trauma or previous surgery.
  • This case is significant as it highlights the importance of accurate and timely diagnosis for effective treatment of keratitis.
  • It marks the first reported instance of keratitis caused by Mycobacteria in Paraguay.
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Background: Leprosy, a chronic infectious disease, is one of the major causes of preventable disability. Early treatment prevents neurological damage and disability.

Aim: To identify prognostic factors of disability in individuals with multibacillary and paucibacillary leprosy who completed a drug treatment between 2011 and 2017 in Paraguay.

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Parental child-focused (RF)-understanding children's behavior as a function of mental states-and parental -understanding, resonating with, and feeling concern for children's emotions-have each been linked to sensitive caregiving and children's attachment security in separate studies, but they have been neither directly compared nor have researchers tested whether they interact in predicting child outcomes. In this article, we offer theoretical perspectives regarding differences between the constructs, potential points of connection, and ways in which these constructs may function together. Then we test these ideas empirically with 2 samples of mothers of school-age children, exploring their unique and interactive associations with parenting sensitivity, children's attachment security, and children's emotion regulation.

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Background: Pityriasis versicolor is a frequent pathology in Paraguay; however, its epidemiology is unknown.

Aim: To determine the frequency of Malassezia species causing pityriasis versicolor and the epidemiological characteristics of the population.

Methods: Samples from patients with a presumptive diagnosis of pityriasis versicolor were collected.

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The lymphomas of mucosa-associated lymphoid tissue (MALT), are uncommon entities, of low grade of malignancy with very infrequent or no lymph node involvement. They represent about 80% of the primary pulmonary lymphomas. The synchronous appearance with lung adenocarcinoma is an extremely rare finding.

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Introduction: Currently, Paraguay has no data on the prevalence of soil-transmitted geohelminth infection in schoolchildren aged 6 to 12 years.

Aim: To determine the prevalence and intensity of infection by Ascaris lumbricoides, Trichuris trichiura and hookworms and the socio-cultural-environmental characteristics of the affected population.

Methods: Descriptive, cross-sectional study, in three semi-tropical climatic zones: continental, semi steppe and humid.

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In this article, we present a platform that allows for the integration of different applications for the follow-up of patients with chronic diseases. We developed two elements: a mobile and a web application. The mobile application allows the capture and processing of vital signs for patients with high blood pressure (hypertension).

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Purpose: In this prospective study, multiplex polymerase chain reaction (PCR) was used to identify genes encoding virulence factors (ica, atlE and mecA) in Coagulase-negative Staphylococcus (CNS) isolates from the ocular microbiota of patients undergoing cataract surgery and to investigate possible changes in the CNS profile due to antibiotic prophylaxis.

Methods: Between 09/2011 and 08/2013, patients undergoing cataract surgery were recruited at the Department of Ophthalmology, National University of Asuncion, Paraguay. In the eye to be operated on, patients received moxifloxacin 0.

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Purpose: Coagulase-negative staphylococci have been reported to be the most frequent cause of bacterial postoperative endophthalmitis. Biofilm formation is the major virulence factor of Staphylococcus epidermidis and is often associated with methicillin resistance. This study aims at evaluating the presence of biofilm-producing and methicillin resistance genes (mecA) in S.

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Introduction: Toxoplasmosis is a worldwide disease; it can cause decreased vision or even blindness. The route of transmission in humans may vary according to the habits of the region; probably the ingestion of raw or undercooked meat is the main source of infection.

Objective: To determine the seroprevalence of toxoplasmosis in an eye clinic, the frequency of ocular toxoplasmosis (OT) and risk habits for acquiring the infection.

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Introduction: Leptospirosis is a serious infectious disease that has been linked to occupational activities such as farmers, sewer workers, garbage collectors, butchers and veterinarians. It is acquired through contact with major reservoirs like rodents, pets, or the environment contaminated by their urine. In Paraguay, there are no published reports on the seroprevalence of leptospirosis related to work activity.

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Background: Dengue is an infection of great global importance with different clinical presentations.

Objective: To establish the seroprevalence of infection by the dengue virus in a district of the Paraguayan Chaco.

Material And Methods: Cross-sectional study in 418 inhabitants of three villages in the district of Villa Hayes, Paraguay, using a probabilistic household sampling, a questionnaire and blood sampling.

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Objective: To estimate the incidence of HIV in the adult population of Paraguay for 2014 and analyze its distribution and associated uncertainty according to risk behavior. METHODS The UNAIDS model was applied according to modes of transmission (MoT). Data were obtained from a detailed review of documents prepared between 1996 and 2013.

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Background: Blepharitis is a very common disease in the ophthalmologic practice generally taking a chronic course with intermittent exacerbations. Several studies have linked the presence of Demodex folliculorum with chronic blepharitis, since the mite has the capacity to perpetuate the follicular inflammatory process. The prevalence of infection by Demodex spp.

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Article Synopsis
  • A 60-year-old man developed mycotic keratitis due to the fungus Lasiodiplodia theobromae after suffering ocular trauma from vegetable matter.
  • Ophthalmological and microbiological evaluations confirmed the presence of the fungus in the corneal ulcer.
  • The patient was treated for 37 days, which controlled the infection, but he ultimately needed a cornea transplant due to scarring, marking the first reported case of this type of keratitis in Paraguay.
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Objective: To compare the efficacy of 3 treatment options in patients with chronic blepharitis.

Methodology: An experimental, randomized, controlled study was conducted on 45 patients (female 67%; Mean age: 40.5 years) diagnosed with chronic blepharitis, in order to compare the effectiveness of three treatment options.

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Purpose: Providing data on the late diagnosis and surgical treatment of patients who underwent surgery for total unilateral congenital cataract. Methods: Systematic retrospective review of the medical record of all patients between 0 and 16 years old with total unilateral congenital cataract who underwent surgery at Fundación Vision between January 2010 and July 2012. Results: Medical records of 37 patients (51 % females) were studied, age was 7.

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Purpose: To determine if the cost was the main barrier to undergo cataract surgery in Paraguay.

Methods: We conducted a cohort study with patients screened in the 2011 Rapid Assessment of Avoidable Blindness (RAAB) who had reported that the cost was the main barrier to undergo cataract surgery in Paraguay. All patients with operable cataract from the RAAB study and with registered telephone numbers were interviewed by telephone and were offered free surgery services.

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