Publications by authors named "Samson Taye"
Background: Embelin is a hydroxybenzoquinone constituent of the Embelia species that has anti-disease properties. However, its toxicity, particularly the , acute, and developmental toxicity profiles, has yet to be thoroughly investigated. Hence, this study aims to assess these toxicity profiles.
View Article and Find Full Text PDFBackground: The leaves of has been used traditionally for the treatment of inflammatory disorders, and pain in various parts of Ethiopia. However, to our knowledge, the analgesic and anti-inflammatory activity of the crude extract and solvent fractions has never been experimentally studied.
Objective: To assess the analgesic and anti-inflammatory activities of leaf extract and solvent fractions in rodent models.
Article Synopsis
- The Vatke plant is widely used in Ethiopia for treating intestinal worms, but its safety and potential teratogenic effects during pregnancy have not been thoroughly studied.
- This study aimed to assess the impact of a hydroalcoholic fruit extract from the Vatke plant on the development of rat embryos and fetuses by evaluating various maternal and fetal health indicators.
- Results indicated that while the extract did not significantly affect most developmental indices, it caused inflammatory reactions and calcifications in the placentas of treated rats, suggesting potential concerns regarding placental health.