Structural Differences in Meibum From Donors After Hematopoietic Stem Cell Transplantations.

Purpose: Meibum is considered to be a key component of tears that serve to protect the eye, and conformational changes in meibum have not been studied extensively within the population of patients who had hematopoietic stem cell transplantation (HSCT). The aim of this study was to determine possible lipid conformational changes in the meibum of patients who had HSCT.

Methods: Participants who had HSCT were randomly sampled for this prospective comparative study.

Absorbance and Light Scattering of Lenses Organ Cultured with Glucose.

Unlabelled: Purpose/Aim: Diabetes is one of the major factors related to cataract. Our aim is to determine if the attenuation of light through glucose treated lenses was due to light scattering from structural changes or absorbance from metabolic changes.

Materials And Methods: Human and rat lenses were cultured in a medium with and without 55 mM glucose for a period of 5 days.

Human Meibum Age, Lipid-Lipid Interactions and Lipid Saturation in Meibum from Infants.

Tear stability decreases with increasing age and the same signs of instability are exacerbated with dry eye. Meibum lipid compositional changes with age provide insights into the biomolecules responsible for tear film instability. Meibum was collected from 69 normal donors ranging in age from 0.

Evaporation and Hydrocarbon Chain Conformation of Surface Lipid Films.

Purpose: The inhibition of the rate of evaporation (R) by surface lipids is relevant to reservoirs and dry eye. Our aim was to test the idea that lipid surface films inhibit R.

Methods: R were determined gravimetrically.