The Effectiveness of Nonsurgical Interventions for Weight Loss Maintenance in Adults: An Updated, GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Context: Today, there are many discussions about the best way to maintain weight and prevent weight regain after a period of weight loss.

Objectives: The aim of this study was to summarize, based on data from randomized clinical trials (RCTs), the impact of nonsurgical interventions for adults' weight loss maintenance.

Data Sources: The Medline (PubMed), Scopus, and Web of Science databases were reviewed during June 2023.

Alcohol consumption and frailty risk: a dose-response meta-analysis of cohort studies.

Background/aims: While previous studies suggest that light-to-moderate alcohol consumption may reduce the frailty risk, the dose-response relationship is still under question. To address the knowledge gap, we conducted a systematic review and dose-response meta-analysis of cohort studies to examine the association of alcohol consumption with the risk of both prefrailty and frailty in adults.

Methods: We searched MEDLINE (Ovid), PubMed and Scopus to identify relevant cohort studies published before 8 May 2024.