Case Report and Review of A Novel Cause of Peritoneal Dialysis Peritonitis in the United Kingdom.

Peritoneal dialysis (PD) peritonitis poses a significant healthcare problem. Most cases are caused by Gram-positive organisms. Newer molecular diagnostic techniques have now enabled identification of previously unrecognized organisms, fully characterizing disease.

Empyema thoracis secondary to community-acquired Panton-Valentine leukocidin (PVL) methicillin-resistant (MRSA) infection.

We report a case of a previously fit middle-aged man presenting to the outpatient setting with unilateral pleural effusion, with minimal symptoms. On subsequent investigations, he was diagnosed with empyema thoracis secondary to Panton-Valentine leukocidin (PVL)-toxin positive community-acquired methicillin-resistant (MRSA). The patient was treated with prolonged antibiotics and pleural drainage, and he remained haemodynamically stable throughout hospital admission.

Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.

Background: Environmental enrichment (EE) in laboratory animals improves neurological function and motor/cognitive performance, and is proposed as a strategy for treating neurodegenerative diseases. EE has been investigated in the R6/2 mouse model of Huntington's disease (HD), where increased social interaction, sensory stimulation, exploration, and physical activity improved survival. We have also shown previously that HD patients and R6/2 mice have disrupted circadian rhythms, treatment of which may improve cognition, general health, and survival.