Design, synthesis, molecular docking, and dynamics studies of novel thiazole-Schiff base derivatives containing a fluorene moiety and the assessment of their antimicrobial and antioxidant activity.

In this study, a series of eighteen fluorene-containing substituted thiazole derivatives were synthesized and characterized spectral analyses. The proposed compounds were screened for their antimicrobial activity, and it was found that compound 2a displayed a significant zone of inhibition (20.3 ± 0.