Publications by authors named "Samira Al Housni"
Article Synopsis
- - Progressive familial intrahepatic cholestasis type 4 (PFIC4) is a newly identified genetic disorder linked to mutations in the tight junction protein 2 gene on chromosome 9q21, often causing cholestasis and potential bleeding issues due to vitamin K deficiency.
- - A neonate presented to the emergency department in 2021 with cholestasis and multiple intracranial bleeds, leading to the discovery of severe coagulopathy.
- - Genetic testing confirmed a homozygous mutation causing PFIC4; the infant received an internal biliary diversion, which resulted in some clinical improvement.
Background and objective Neonatal hypoglycemia (NH) is one of the most common causes of admission to the neonatal intensive care unit (NICU). Persistent NH despite adequate feeding and intravenous dextrose may often require medications to maintain normal blood glucose levels (BGL). Several medications are used in the management of persistent NH, such as glucagon, diazoxide, and octreotide.
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