Pulmonary manifestations in inflammatory bowel disease: a prospective study.

Background: Although pulmonary abnormalities have been recognized in patients with inflammatory bowel diseases (IBD), their prevalence and clinical significance are not known.

Aim: To study the prevalence and clinical significance of pulmonary abnormalities in patients with IBD.

Methods: Ninety-five non-consecutive patients with IBD (12 Crohn's disease, 83 ulcerative colitis; mean age 41.

Self-reported treatment adherence in inflammatory bowel disease in Indian patients.

Introduction: Non-adherence to medical therapy is emerging as an important determinant of relapse in patients with inflammatory bowel disease (IBD).

Aim: To find the prevalence of and reasons for nonadherence to medical therapy in Indian patients with IBD and its correlation with disease outcome.

Methods: In this cross-sectional study, we checked for adherence to treatment in 127 patients with IBD (117 ulcerative colitis and 10 Crohn's disease) using a questionnaire that inquired into frequency of missed doses, causes for missed doses, and its relation to relapse of disease.

Prevalence of abnormal radiological findings in health care workers with latent tuberculosis infection and correlations with T cell immune response.

Background: More than half of all health care workers (HCWs) in high TB-incidence, low and middle income countries are latently infected with tuberculosis (TB). We determined radiological lesions in a cohort of HCWs with latent TB infection (LTBI) in India, and determined their association with demographic, occupational and T-cell immune response variables.

Methodology: We obtained chest radiographs of HCWs who had undergone tuberculin skin test (TST) and QuantiFERON-TB Gold In Tube (QFT), an interferon-gamma release assay, in a previous cross-sectional study, and were diagnosed to have LTBI because they were positive by either TST or QFT, but had no evidence of clinical disease.

Risk factors for acute myocardial infarction in a rural population of central India: a hospital-based case-control study.

Background: There is a paucity of data on the relative importance of various traditional risk factors for coronary artery disease among rural Indians. We conducted a prospective case-control study to determine the risk factors for acute myocardial infarction in a rural population of central India.

Methods: We recruited 111 consecutive patients admitted to our hospital with a first episode of acute myocardial infarction and 222 age- and sex-matched controls.