Publications by authors named "Samir Khatib"

Article Synopsis
  • Osteogenesis imperfecta (OI) is a bone disorder primarily caused by genetic mutations in type I collagen genes, with most cases being autosomal dominant.
  • Recent findings have established a connection between the Mesoderm Development LRP Chaperone (MESD) and autosomal recessive OI, highlighting various biallelic pathogenic variants linked to severe deformities and recurrent fractures.
  • This study expands the understanding of MESD’s role in WNT signaling, emphasizing its critical function in bone formation and pointing out the novel pathogenic variants that can lead to severe neonatal outcomes.
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Background: Streptococcus agalactiae (group B Streptococcus) is beta-hemolytic, catalase negative, gram-positive cocci, recognized as main bacterial pathogen causing infections in newborns, infants, adults, and elderly people around the world. The aim of this study is to investigate group B Streptococcus samples recovered from invasive patients and determine serotype, virulent genes, and antibiotic-resistant profile of Streptococcus agalactiae in Palestine.

Methods: A total of 95 group B Streptococcus strains were isolated from neonates, infants, pregnant and non-pregnant women and males at Arabcare Hospital Laboratory, Palestine, between the period of June 2018 and September 2020.

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The first "Out of Africa" migrations represent a seminal event in the history of humankind. At the gates of Europe, the first appearance of Hominins is recorded in Georgia, 1.8 million years ago (Ma); however, the picture of migration across the continent remains incomplete.

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Refined radio-isotopic dating techniques have been applied to Orgnac 3, a Late Acheulean and Early Middle Palaeolithic site in France. Evidence of Levallois core technology appeared in level 4b in the middle of the sequence, became predominant in the upper horizons, and was best represented in uppermost level 1, making the site one of the oldest examples of Levallois technology. In our dating study, fourteen speleothem samples from levels 7, 6 and 5b, were U/Th-dated.

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