- Non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious intestinal issues, including diaphragm disease, which leads to thick, narrow strictures and potential bowel obstruction.
- Diaphragm disease is often difficult to diagnose and can be treated conservatively by stopping NSAID use, as demonstrated in a case of a 59-year-old woman who experienced abdominal pain.
- With the increasing use of NSAIDs, healthcare providers should consider diaphragm disease when diagnosing patients with vague abdominal pain or obstruction symptoms related to chronic NSAID use.