White Matter Lesions: Prevalence and Clinical Phenotype in Asymptomatic Individuals Aged ≥50 Years.

Background: To assess the prevalence of early confluent/confluent white matter lesions (ec/cWMLs) in asymptomatic individuals aged ≥50 years and to identify associated clinical phenotypes.

Methods: Cross-sectional analysis of 141 asymptomatic individuals aged ≥50 years assessed at an outpatient department in France. Brain magnetic resonance imaging was rated using the Fazekas scale.

[Deglutition disorders in elderly patients].

Deglutition disorders are frequent in elderly patients and can lead to serious consequences in terms of morbidity and mortality. Despite an easy screening test with the water, they are ignored or underestimated. Moreover, early detection and treatment focused essentially on the adaptation of textures, postures as well as the provision of information and training to all the people involved in feeding the elderly person require few resources and provide a real benefit.

[Utility of soluble transferrin receptor measurement for early diagnostic of iron deficiency in elderly hospitalized patients].

Diagnosis of iron deficiency is not easily performed in inflammatory situation as usually encountered in elderly hospitalized patients (>70 years old). At first, we determined serum soluble receptor transferrin (RsTf), RsTf/serum ferritin ratio (RsTf-F index) and biochemical and haematological values used to evaluate iron status, in iron-depleted subjects (ferritinemia≤50 μg/L) (group 2) (n=22, 82±7 years) or not (group 1, reference group) (n=18, 82±6 years), without inflammatory diseases. Relevance of the biological parameters to diagnose iron deficiency was evaluated (ROC curve) and a cut-off value of RsTf-F (>1.