Spasmolytic and anti-inflammatory effects of constituents from Hertia cheirifolia.

A sesquiterpenoid Bakkenolide (1), and two steroids, (3beta, 22E)-Stigmasta-5, 22-diène-3-ol (Stigmasterol) (2) and stigmasterol 3beta-glucoside (3), isolated from the Hertia cheirifolia (L.) chloroform extract, were evaluated respectively for their spasmolytic and anti-inflammatory activities. We note that these natural products were isolated and purified for the first time from the specie Hertia cheirifolia.

Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli.

A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3'-formyl-5'-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-alpha-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.

Antimicrobial and cytotoxic activity of Marrubium alysson and Retama raetam grown in Tunisia.

Antibacterial and antifungal activities of extracts obtained from M. alysson, R. raetam were tested using a solid medium technique.

Mutagenic, antimutagenic and antioxidant activities of a new class of beta-glucoside hydroxyhydroquinone from Anagallis monelli growing in Tunisia.

A new skeleton of an O-heteroside natural substance named zinolol, the first representative of a new class of aminated hydroxyhydroquinone, has been isolated from the whole plant Anagallis monelli. Its structure has been established by one and two dimensional NMR spectroscopic procedures. Antioxidant, mutagenic, antimutagenic activities were realised and positive results were recorded.

Antimicrobial and antioxidant activities of the methanolic extracts of three Salvia species from Tunisia.

This study examines the in vitro antimicrobial and antioxidant activities of the methanolic extracts of three Salvia species from Tunisia: Salvia aegyptiaca L., S. argentea L.

[Which place for VDD mode single electrode pacemaker?].

VDD mode single electrode pacemaker is a technique of cardiac stimulation which preserves auriculo-ventricular synchronism using a single electrode. Its importance has decreased because of the numerous satisfactions previous by the DDD mode. We describe our experience with this mode and we discuss the advantages, limits and indications of this mode of cardiac stimulation.