Synthesis of New 1-1,2,3-Triazole Analogs in Aqueous Medium "" Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors.

A series of novel 1-1,2,3-triazole analogs () were synthesized chemistry and Suzuki-Miyaura cross-coupling reaction in aqueous medium. The compounds were evaluated for their carbonic anhydrase-II enzyme inhibitory activity . The synthesis of triazole was accomplished using ()-(-) ethyl lactate as a starting material.

Secondary metabolites from the resins of Aloe vera and Commiphora mukul mitigate lipid peroxidation.

Oxidative stress is often considered detrimental for cellular processes and damaging for the lipid bi-layer. Counteracting such stresses with the aid of nature-based chemical constituents can be an ideal therapeutic approach. The current study aimed to investigate the chemical constituents of resins derived from the well-known Aloe vera and less known Commiphora mukul trees and their effect in mitigating the lipid peroxidation (LPO) process.