Cerebral oxygen and glucose metabolism in patients with mitochondrial m.3243A>G mutation.

The m.3243A>G mutation is the most common pathogenic mutation in mitochondrial DNA. It leads to defective oxidative phosphorylation, decreased oxygen consumption and increased glucose utilization and lactate production in vitro.

Vortex pump for dilute bose-einstein condensates.

The formation of vortices by topological phase engineering has been realized experimentally to create the first two- and four-quantum vortices in dilute atomic Bose-Einstein condensates. We consider a similar system, but in addition to the Ioffe-Pritchard magnetic trap we employ an additional hexapole field. By controlling cyclically the strengths of these magnetic fields, we show that a fixed amount of vorticity can be added to the condensate in each cycle.