Publications by authors named "Sami Fares"
Background: Open offers (OOs) in liver transplantation (LT) result from bypassing the traditional allocation system. Little is known about the trends of OOs or the differences in donor/recipient characteristics compared to traditionally placed organs. We aim to quantify modern practices regarding OOs and understand NMP's impact, focusing on social determinants of health (SDH), cost, and graft-associated risk.
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- The study aimed to evaluate the costs and complications associated with liver transplantation (LT) utilizing normothermic machine perfusion (NMP) compared to static cold storage (SCS).
- A total of 803 liver transplant recipients were analyzed, showing that NMP reduced complications like the need for relaparotomy and renal therapy, especially in donations after circulatory death (DCD).
- Although NMP increased organ acquisition costs, it led to lower 90-day pretransplant costs due to shorter waiting times, resulting in comparable overall costs between NMP and SCS cohorts.
Introduction: Circulating tumor DNA (ctDNA) is emerging as a promising, non-invasive diagnostic and surveillance biomarker in solid organ malignancy. However, its utility before and after liver transplant (LT) for patients with primary and secondary liver cancers is still underexplored.
Methods: Patients undergoing LT for hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and colorectal liver metastases (CRLM) with ctDNA testing were included.
Introduction: Type 2 diabetes (T2D) is a chronic medical condition that results in significant health implications and reduced life expectancy. The International Diabetes Federation (IDF) estimated that in 2021, 51.8% of all deaths of people under 60 years old in the Middle East and North Africa (MENA) region were related to diabetes.
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