Publications by authors named "Sami Aziz"
Article Synopsis
- Pancreatic cancer (PC), especially pancreatic ductal adenocarcinoma (PDAC), is a highly aggressive and difficult-to-treat disease with a high mortality rate.
- Existing treatment options for PDAC are inadequate, making personalized medicine essential for effective therapy, alongside a deeper understanding of how PDAC develops.
- The review discusses the role of the PI3K/AKT/mTOR signaling pathway in PDAC's progression, presents current clinical data on targeting this pathway, and suggests potential combination therapies that could improve patient outcomes.
Limited data on the clinical management of drug-drug interactions between triazoles and Cystic Fibrosis transmembrane conductance regulator (CFTR) modulators are available. We retrospectively evaluated azole target attainment and dose adaptations in patients from two Dutch CF centres concomitantly receiving triazoles and CFTR modulators. In total, 21 patients with 59 triazole trough concentrations were evaluated.
View Article and Find Full Text PDFIdentification and molecular characterization of Babesia gibsoni proteins with potential antigenic properties are crucial for the development and validation of the serodiagnostic method. In this study, we isolated a cDNA clone encoding a novel B. gibsoni 76-kDa protein by immunoscreening of the parasite cDNA library.
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