Publications by authors named "Sami Alradhi"
Background Hemophagocytic lymphohistiocytosis (HLH) is an uncommon, potentially fatal condition caused by high immune activation. The present study aimed to identify the clinical manifestations, geographic distribution, and associated pathogenic genetic mutations of HLH in Saudi Arabia. Method A retrospective cross-sectional study was conducted at King Fahad Medical City (KFMC), with a total of 59 patients diagnosed with HLH in the period between 2006 and 2018.
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- * A key issue in CHS is neutropenia, or low neutrophil count, which can persist despite treatments such as chemotherapy and stem cell transplantation.
- * The case report discusses an 8-year-old girl with CHS whose severe neutropenia improved significantly after treatment with Granulocyte-colony stimulating factor (G-CSF), leading to a stable condition and consideration for bone marrow transplantation.