Publications by authors named "Samer Habeel"
Article Synopsis
- Infectious keratitis in children under two years old can cause severe issues like vision loss and blindness, but data on this age group is limited, prompting a study to examine its causes and treatment.
- The study reviewed 57 cases from July 2005 to December 2022, revealing that most affected children had predisposing factors such as prior eye trauma or surgery, with Pseudomonas aeruginosa being the most common pathogen.
- Findings showed that while medical treatments were effective against infections, many children still required surgical intervention, indicating a need for improved management strategies in this vulnerable population.
Ocular trauma is an important cause of monocular blindness worldwide. Injury to the lens after blunt or penetrating trauma is common and can result in vision impairment. Selecting the most appropriate therapeutic approaches depends on factors such as patients' age, mechanism of trauma, and underlying clinical conditions.
View Article and Find Full Text PDFGlioblastoma (GBM), the most aggressive form of brain cancer, has witnessed very little clinical progress over the last decades, in part, due to the absence of effective drug delivery strategies. Intravenous injection is the least invasive drug delivery route to the brain, but has been severely limited by the blood-brain barrier (BBB). Inspired by the capacity of natural proteins and viral particulates to cross the BBB, we engineered a synthetic protein nanoparticle (SPNP) based on polymerized human serum albumin (HSA) equipped with the cell-penetrating peptide iRGD.
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