Prevalence of laryngeal irritation signs associated with reflux in asymptomatic volunteers: impact of endoscopic technique (rigid vs. flexible laryngoscope).

Objectives: The objectives of this study were to 1) determine the prevalence of ENT findings in the normal asymptomatic population and 2) to compare findings between flexible and rigid laryngoscopes in an attempt to increase specificity of diagnosis of reflux in endoscopic laryngeal examinations.

Study Design: Prospective study.

Methods: Fifty-two nonsmoker volunteers (24 male, 28 female), mean age of 42.

The role of esophageal pH monitoring in symptomatic patients on PPI therapy.

Background: Ambulatory pH monitoring while on therapy is often recommended in gastroesophageal reflux disease (GERD) patients with continued symptoms. However, to date, little data exist to justify this indication.

Aim: To assess the role of pH monitoring in symptomatic patients despite aggressive therapy with typical or extra esophageal GERD.