Laparoscopic Right Donor Nephrectomy: A Two-Center Comparative Study.

Introduction As the field of laparoscopic living donor nephrectomy (LLDN) has progressed over the years, there has been a growing emphasis on optimizing surgical techniques and outcomes to ensure the safety and well-being of living kidney donors. The early experiences with right LLDN, marked by challenges and concerns such as high conversion rates to open surgery and early graft loss due to technical reasons, prompted a reevaluation of the approach toward right-sided donor nephrectomies. In this article, we aim to compare the safety and efficacy of right LLDN to left LLDN performed in our centers and to provide valuable insights that can ultimately enhance patient outcomes and ensure the well-being of living organ donors.

Role of allograft nephrectomy following kidney graft failure: preliminary experience with pre-operative angiographic kidney embolization.

Introduction: Allograft nephrectomy (AN) is not without morbidity following graft failure (GF) in kidney transplantation (KT).

Methods: Single center retrospective review of all adult patients undergoing AN following KT, including a subset of patients who underwent pre-operative angiographic kidney embolization (PAKE).

Results: Over a 104 month period, 853 adult patients underwent deceased donor KT.

Treatment options for renal cell carcinoma in renal allografts: a case series from a single institution.

Renal cell carcinoma (RCC) is more common in renal transplant and dialysis patients than the general population. However, RCC in transplanted kidneys is rare, and treatment has previously consisted of nephrectomy with a return to dialysis. There has been recent interest in nephron-sparing procedures as a treatment option for RCC in allograft kidneys in an effort to retain allograft function.

Evolving experience using kidneys from deceased donors with terminal acute kidney injury.

Background: Kidney transplantation from deceased donors with terminal acute kidney injury (AKI) is not widely accepted.

Study Design: Acute kidney injury donor kidneys were defined by a doubling of the donor's admission serum creatinine (SCr) level and a terminal SCr level >2.0 mg/dL before organ recovery.

Pancreas transplantation: lessons learned from a decade of experience at Wake Forest Baptist Medical Center.

This article reviews the outcome of pancreas transplantations in diabetic recipients according to risk factors, surgical techniques, and immunosuppression management that evolved over the course of a decade at Wake Forest Baptist Medical Center. A randomized trial of alemtuzumab versus rabbit anti-thymocyte globulin (rATG) induction in simultaneous kidney-pancreas transplantation (SKPT) at our institution demonstrated lower rates of acute rejection and infection in the alemtuzumab group. Consequently, alemtuzumab induction has been used exclusively in all pancreas transplantations since February 2009.

Lessons learned from a single center's experience with 134 donation after cardiac death donor kidney transplants.

Background: Reports of kidney transplantation from donation after cardiac death (DCD) donors describe high rates of delayed graft function (DGF).

Study Design: From April 1, 2003 to October 17, 2010, we performed 134 kidney transplants from DCD donors including 120 (90%) from standard-criteria donors (SCDs) and 14 (10%) from expanded-criteria donors (ECDs). Nineteen kidneys were recovered from donors managed with extracorporeal interval support for organ retrieval (EISOR) after cardiac arrest to minimize ischemic injury.

Novel concepts in the treatment of localized renal cell carcinoma.

The understanding of renal cell carcinoma has undergone significant advances in the past several years. These have included advances in imaging procedures and surgical approaches, allowing for more precise staging, and individualized approaches to therapy. Furthermore, there has been an increase in the diagnosis of incidental tumors and currently the majority of RCCs are incidentally diagnosed on routing imaging procedures.