Background: The liver is crucial for maintaining normal metabolism in the body. Various substances, such as toxic chemicals, drugs, and alcohol, can damage hepatocyte cells, leading to metabolic imbalances.
Aim: The experiment aimed to determine the efficacy of seed oil (LSS) as a hepatoprotective agent against acute hepatotoxicity triggered by carbon tetrachloride (CCl).
Background: Doxorubicin (DOX) is a chemotherapeutic drug applied clinically for the remedy of cancer, but its possibly life-threatening cardiotoxicity effects remain a concern.
Aim: After that, this study evaluates the cardioprotective impacts of (LSS) oil on DOX induced cardiomyopathy in rats.
Methods: Wistar male rats ( = 28, weighting 190-210 g) were arbitrarily allocated into four equal groups.
Lignin nanoparticles emerged as a promising alternative for drug delivery systems owing to their biodegradability and bioactive properties. This study investigated the antimicrobial activity of the ethanolic extract of loaded lignin nanoparticles (OB-LNPs) and seed oil-loaded lignin nanoparticles (LS-LNPs) to find a solution for antimicrobial resistance. OB-LNPs and LS-LNPs were tested for their antimicrobial potential against , , , , , , , and .
View Article and Find Full Text PDFAntimicrobial resistance poses considerable issues for current clinical care, so the modified use of antimicrobial agents and public health initiatives, coupled with new antimicrobial approaches, may help to minimize the impact of multidrug-resistant (MDR) bacteria in the future. This study aimed to evaluate the antimicrobial, antioxidant, and immunomodulatory activities of , , and their chitosan nanocomposites against extensive drug-resistant (XDR) and vancomycin-resistant (VRSA) using both in vitro and in vivo assays. The in vitro antimicrobial susceptibilities of and VRSA strains revealed 100% sensitivity to imipenem (100%).
View Article and Find Full Text PDFThis study aimed to evaluate the efficacy of cefquinome in treatment and controlling of experimentally infected broiler chickens, in addition of detection of its residues using High performance liquid chromatography (HPLC). In this study, 150 one-day old Cobb broiler chicks were used. On the 14 day chicks experimentally infected and divided into 3 equal groups (50 each); control group (G1) non-infected, non-treated, (G2) infected with non treated, (G3) infected with , cefquinome treated.
View Article and Find Full Text PDFBackground And Aim: Gold nanorods (AuNRs) have gained much attention recent years due to their promising optical and chemical properties and are hence used in applied research and industrial nanotechnology. This study was designed to investigate the effect of gold nanoparticle shape (Gold nanorods vs. gold nanosphere) on immune response in rabbit.
View Article and Find Full Text PDFIn this study, we investigated the effect of acute administration of gold nanorods (AuNRs) on testicular function, sexual hormones, and oxidative stress parameters in male albino rats. Forty mature male albino rats were divided into two equal groups (n = 20/each). The first group received 1 ml saline solution intraperitoneally (i.
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