Publications by authors named "Sameerah Al-Shehri"
Article Synopsis
- Hypothyroid patients on levothyroxine face challenges with medication adherence during Ramadan due to fasting, leading to a study on the best administration times.
- The study found that compliance was lowest when taking the medication 3-4 hours after the iftar meal, while most patients preferred taking it 30 minutes before iftar.
- Results showed a significant increase in TSH and FT4 levels after Ramadan, but the timing of levothyroxine intake did not affect these hormone levels, suggesting flexibility in administration timing.
Context: Dyshormonogenesis due to genetic defect in thyroglobulin (Tg) synthesis and secretion can lead to congenital hypothyroidism.
Objectives: The aim of the study was to analyze the TG gene for the presence of mutations and to study the underlying mechanisms leading to dyshormonogenesis.
Cases: Two siblings aged 25 and 31 yr presented with recurrent goitrous hypothyroidism with undetectable serum Tg.