Publications by authors named "Sameer Pandya"
Capacity assessment for EHR-based medical device post-market surveillance for synthetic mid-urethral slings among women with stress urinary incontinence: a NEST consortium study.
BMJ Surg Interv Health Technol
February 2025
Objectives: To evaluate the feasibility for use of electronic health record (EHR) data in conducting adverse event surveillance among women who received mid-urethral slings (MUS) to treat stress urinary incontinence (SUI) in five health systems.
Design: Retrospective observational study using EHR data from 2010 through 2021. Women with a history of MUS were identified using common data models; a common analytic code was executed at each site.
Article Synopsis
- Researchers studied 9,902 SARS-CoV-2 infections over two years to understand how genetic variations in the virus and factors like host age and vaccination status affect viral copies.
- They used a genome-wide association study (GWAS) to find specific genetic changes (SNPs) in the virus correlated with higher or lower viral copies, particularly noting interactions between these SNPs.
- The study revealed that SNPs linked to higher viral loads were mainly seen in Delta and Omicron variants, while those linked to lower loads were found in Omicron BA.1, suggesting the potential for GWAS to analyze other pathogens and their variants.
The advent of minimal pain tumescent local anesthesia injection has improved patient safety by eliminating the need for sedation for many wide awake operations, especially in patients with significant medical comorbidities. Modified radical mastectomy (MRM) for breast cancer is commonly performed under general anesthesia as it requires the dissection of the entire breast and an ipsilateral axillary lymph node dissection (ALND). General anesthesia has been shown to have a high risk in patients with severe medical comorbidities.
View Article and Find Full Text PDFObjective: We aimed to discover computationally-derived phenotypes of opioid-related patient presentations to the ED via clinical notes and structured electronic health record (EHR) data.
Methods: This was a retrospective study of ED visits from 2013-2020 across ten sites within a regional healthcare network. We derived phenotypes from visits for patients ≥18 years of age with at least one prior or current documentation of an opioid-related diagnosis.