Publications by authors named "Sambhavana Chauhan"

Article Synopsis
  • Tomato plants expressing dsRNA targeting Fusarium oxysporum f. sp. lycopersici (Fol) have been developed, enhancing their resistance to the fungal infection and significantly reducing disease symptoms.
  • Through RNA interference (RNAi) technology, transgenic tomatoes were created to silence specific Fol genes associated with disease, leading to a substantial decrease in Fol colonization and improved plant health.
  • The study confirms that host-induced gene silencing (HIGS) effectively provides durable resistance against Fusarium wilt in tomatoes, suggesting a viable biofungicide strategy without harming the plant’s overall photosynthetic function.
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Fusarium oxysporum f. sp. lycopersici (Fol) is majorly responsible for causing vascular wilt disease in tomato by blocking transpirational pull, thereby interfering and suppressing overall host immune response.

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RNA interference (RNAi) is a universal phenomenon of RNA silencing or gene silencing with broader implications in important physiological and developmental processes of most eukaryotes, including plants. Small RNA (sRNA) are the critical drivers of the RNAi machinery that ensures down-regulation of the target genes in a homology-dependent manner and includes small-interfering RNAs (siRNAs) and micro RNAs (miRNAs). Plant researchers across the globe have exploited the powerful technique of RNAi to execute targeted suppression of desired genes in important crop plants, with an intent to improve crop protection against pathogens and pests for sustainable crop production.

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