Publications by authors named "Samara Khan"
Neuregulin1 (Nrg1) signaling is critical for neuronal development and function from fate specification to synaptic plasticity. Type III Nrg1 is a synaptic protein which engages in bidirectional signaling with its receptor ErbB4. Forward signaling engages ErbB4 phosphorylation, whereas back signaling engages two known mechanisms: (1) local axonal PI3K-AKT signaling and (2) cleavage by γ-secretase resulting in cytosolic release of the intracellular domain (ICD), which can traffic to the nucleus (Bao et al.
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- The study examines how the demographic match between medical students and their preceptors influences the students' specialty choices during their clinical clerkships.
- A survey of 84 graduating medical students showed that female and non-Caucasian students place significantly higher importance on gender and race/ethnicity concordance with their preceptors than their male and Caucasian counterparts.
- Results indicated that Caucasian females valued gender concordance most, while non-Caucasian females prioritized both gender and race/ethnicity concordance in their selection of medical specialties.
Background: While there may be an association between race, tumor size, and survival in patients with cervical squamous cell carcinoma (SCC), evidence on the effect of race on the association between tumor size at diagnosis and survival is limited. Our study evaluated whether race modifies the association between tumor size and 10-year survival in cervical SCC.
Methods: This non-concurrent cohort study with the Surveillance, Epidemiology, and End Results (SEER) database included women diagnosed with cervical SCC between 2004-2018.