Publications by authors named "Samara Bonfante"
Effects of oestrogen deficiency and 17β-estradiol therapy on bone healing in calvarial critical size defects treated with bovine bone graft.
Arch Oral Biol
April 2015
Objective: To histomorphometrically analyze the effect of ovariectomy-induced oestrogen deficiency and 17β-estradiol therapy on bone healing of surgically created critical-size defects (CSDs) treated with bovine bone graft (BBG).
Methods: Forty-eight female rats were randomly assigned to the following 3 experimental groups (n=16): sham-operated animals (SHAM), ovariectomized animals (OVX) and ovariectomized animals treated with oestrogen (OVX+E2). OVX+E2 animals received daily subcutaneous injections of 17β-estradiol (20μg/kg) from 8 days after ovariectomy until euthanasia.
Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography.
Oral Surg Oral Med Oral Pathol Oral Radiol
October 2012
Article Synopsis
- The study aimed to compare the effectiveness of a collagen-based membrane against no treatment in promoting guided bone regeneration, using 3D computerized microtomography (μCT).
- Defects were surgically created in beagle dogs, with some treated with the membrane and others left untreated, and samples were taken at 2 and 16 weeks post-surgery for analysis.
- Results indicated that the membrane significantly improved bone regeneration after 16 weeks compared to both the 2-week results and the untreated group.
Background: Very limited information is available from in vivo studies about whether smoking and/or nicotine affect gingival tissues in the absence of plaque. The purpose of this study is to evaluate the effect of the systemic administration of nicotine in the proliferation and counting of fibroblast-like cells in the gingival tissue of rats.
Methods: Thirty adult male Wistar rats were randomly assigned into two groups to receive subcutaneous injections of a saline solution (control group = group C) or nicotine solution (group N; 3 mg/kg) twice a day.
Background: The aim of this study was to evaluate histologically and histometrically the influence of photodynamic therapy (PDT) as an adjuvant treatment on induced periodontitis in rats with diabetes.
Methods: Two hundred forty rats were divided evenly into two groups: non-diabetic (ND; n = 120) and alloxan diabetic (D; n = 120). Periodontal disease was induced in both groups at the first mandibular molar.
Purpose: The aim of this study was to perform qualitative and quantitative analyses of the effect of nicotine on autogenous bone block grafts and to describe events in the initial healing phase and the differences in the repair processes between animals exposed to nicotine and controls.
Materials And Methods: Forty-eight female Wistar rats were randomly divided into 2 groups, the nicotine group and the saline group. All animals received either nicotine (3 mg/kg) or saline 4 weeks before the surgical procedure and continued to receive nicotine from surgery to sacrifice at 7, 14, or 28 days.
Purpose: The aim of this study was to evaluate quantitatively and qualitatively the influence of estrogen deficiency on autogenous bone block grafts in aged ovariectomized rats.
Materials And Methods: Fifty 12-month-old female Wistar rats were used in the study. They were divided into 2 groups, an ovariectomized group and a sham-operated group.
Background: Cigarette smoking has long been recognized as a risk factor for periodontal disease. The aim of this study was to perform quantitative and qualitative analyses of bone loss in the furcation region of periodontally healthy rats after daily systemic administration of nicotine or saline solution.
Methods: Thirty adult male Wistar rats were assigned randomly to twice daily subcutaneous injections of saline solution (control, group C) or nicotine (group N).
Background: Excisional biopsies of gingival overgrowths, performed with safety margins, frequently result in mucogingival defects. These defects may produce esthetic problems and increase the chances of dentin hyperesthesia and its possibility of hindering oral hygiene.
Methods: Two clinical cases are reported in which gingival overgrowths were removed by excisional biopsy, resulting in unsightly defects.