The effect of regular hemodialysis on the nutritional status of children with end-stage renal disease.

Growth failure is one of the most common and profound clinical manifestation of chronic kidney disease (CKD) in infants, children and adolescents. The aim of this study was to assess the nutritional status of Egyptian children with end-stage renal disease (ESRD) on regular hemodialysis (HD). The study included 50 Egyptian children with ESRD on regular HD, following-up at the Pediatric Nephrology unit, Cairo University.

Iron deficiency anemia in an Egyptian pediatric population: a cross-sectional study.

Objective: The aim of this study is to assess the frequency of iron deficiency anemia (IDA) and associated sociodemographic factors among children between 6 months and 12 years of age.

Materials And Methods: This cross-sectional study enrolled 300 children from June 2011 to June 2012 visiting the pediatric outpatient clinics of Al-Fayoum University Hospital. Data were collected using a structured interview questionnaire.

Adiponectin: an adipocyte-derived hormone, and its gene encoding in children with chronic kidney disease.

Background: The prevalence of cardiovascular disease (CVD) and inflammation is high in patients with chronic kidney disease (CKD). Adiponectin (ADPN) is an adipocytokine that may have significant anti-inflammatory and anti-atherosclerotic effects. Low adiponectin levels have previously been found in patients with high risk for CVD.

Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease.

Aim And Methods: We investigated the association between polymorphisms of the angiotensin converting enzyme-1 (ACE-1) and angiotensin II type one receptor (AT1RA1166C) genes and the causation of renal disease in 76 advanced chronic kidney disease (CKD) pediatric patients undergoing maintenance hemodialysis (MHD) or conservative treatment (CT). Serum ACE activity and creatine kinase-MB fraction (CK-MB) were measured in all groups. Left ventricular mass index (LVMI) was calculated according to echocardiographic measurements.

Systemic lupus erythematosus in Egyptian children.

The aim of the study was to study the characteristics of systemic lupus erythematosus (SLE) in the Egyptian population, comparing it to other populations. We retrospectively studied 207 patients with SLE diagnosed between 1990 and 2005. We obtained clinical features and laboratory data and analyzed them statistically.

Central venous catheters as a vascular access modality for pediatric hemodialysis.

Background: The use of hemodialysis catheters is an essential component of dialysis practice. Children are particularly likely to require multiple courses of dialysis over their lifetime, hence the repeated need for vascular access. These catheters remain a significant source of morbidity and mortality.